Evidence map›Paper›PMID 33585918›Full record

Trial reportThe journals of gerontology. Series A, Biological sciences and medical sciences2021

Ratings of Perceived Exertion During Walking: Predicting Major Mobility Disability and Effect of Structured Physical Activity in Mobility-Limited Older Adults.

Erta Cenko, Haiying Chen, Thomas M Gill, Nancy W Glynn, Rebecca M Henderson, Abby C King, Marco Pahor, Peihua Qiu, Alvito Rego, Kieran F Reid and 4 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in The journals of gerontology. Series A, Biological sciences and medical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Walking netEuropean journal of applied physiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Erta CenkoDepartment of Epidemiology, University of Florida, Gainesville, USA.ORCID 0000-0002-7402-6495
Haiying ChenDepartment of Biostatistics and Data Science, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Thomas M GillDepartment of Internal Medicine, Division of Geriatric Medicine, Yale School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0002-6450-0368
Nancy W GlynnDepartment of Epidemiology, University of Pittsburgh, Pennsylvania, USA.
Rebecca M HendersonDepartment of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.ORCID 0000-0003-1176-8544
Abby C KingDepartment of Health Research and Policy, Stanford University, California, USA.
Marco PahorDepartment of Aging and Geriatric Research, University of Florida, Gainesville, USA.
Peihua QiuDepartment of Biostatistics, University of Florida, Gainesville, USA.
Alvito RegoDivision of General Internal Medicine and Geriatrics, Northwestern University, Chicago, Illinois, USA.
Kieran F ReidNutrition, Exercise Physiology and Sarcopenia Lab, Tufts University, Boston, Massachusetts, USA.
Catrine Tudor-LockeCollege of Human and Health Services, UNC Charlotte, North Carolina, USA.
Vincenzo ValianiDepartment of Interdisciplinary Medicine, Università degli Studi di Bari Aldo Moro, Italy.
Lu YouDepartment of Biostatistics, University of Florida, Gainesville, USA.
Todd M ManiniDepartment of Aging and Geriatric Research, University of Florida, Gainesville, USA.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
UF FIELD CENTERU01AG022376 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI PAHOR, MARCO · 2003 to 2015
$83.3M
Yale Study Support Suite (YES3): Dashboard and Web Portal Software Supporting Research Workflow through integrated, customizable REDCap External ModulesP30AG021342 · NIA · YALE UNIVERSITY · PI Albert C Shaw · 2002 to 2026
$37.9M
Wake Forest Claude D. Pepper OAIC - RenewalP30AG021332 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Denise Kathryn Houston · 2002 to 2026
$36.4M
VARIABILITY, STABILITY & SMOOTHNESS OF WALKINGP30AG024827 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Caterina Rosano · 2004 to 2026
$28.6M
University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI Peihua Qiu · 2007 to 2026
$22.8M
ACADEMIC LEADERSHIP AWARD IN DISABILITY AND DISABLING DISORDERSK07AG043587 · NIA · YALE UNIVERSITY · PI GILL, THOMAS MICHAEL · 2013 to 2017
$645k
NCATS NIH HHS UL1 TR001863NIA NIH HHS K07 AG043587NIA NIH HHS P30 AG021332NIA NIH HHS P30 AG021342NIA NIH HHS P30 AG024827NIA NIH HHS P30 AG028740NIA NIH HHS U01 AG022376NIA NIH HHS UO1 AG22376NIH HHS 1 P30 AG028740NIH HHS 3U01AG022376-05A2SNIH HHS P30AG021342
6 · The paper itself

Abstract

backgroundThis study evaluated the association between ratings of perceived exertion (RPE) of walking and major mobility disability (MMD), as well as their transitions in response to a physical activity (PA) compared to a health education (HE) program.

methodsOlder adults (n = 1633) who were at risk for mobility impairment were randomized to structured PA or HE programs. During a 400 m walk, participants rated exertion as "light" or "hard." An MMD event was defined as the inability to walk 400 m. MMD events and RPE values were assessed every 6 months for an average of 2.6 years.

resultsParticipants rating their exertion as "hard" had a nearly threefold higher risk of MMD compared with those rating their exertion as "light" (HR: 2.61, 95% CI: 2.19-3.11). The association was held after adjusting for disease conditions, depression, cognitive function, and walking speed (HR: 2.24, 95% CI: 1.87-2.69). The PA group was 25% more likely to transition from "light" to "hard" RPE than the HE group (HR: 1.25, 95% CI: 1.05-1.49). Additionally, the PA group was 27% (HR: 0.73, 95% CI: 0.55 - 0.97) less likely to transition from a "hard" RPE to inability to walk 400 m and was more likely to recover their ability to walk 400 m by transitioning to a "hard" RPE (HR: 2.10, 95% CI: 1.39-3.17) than the HE group.

conclusionsOlder adults rating "hard" effort during a standardized walk test were at increased risk of subsequent MMD. A structured PA program enabled walking recovery, but was more likely to increase transition from "light" to "hard" effort, which may reflect the greater capacity to perform the test.

Indexed as

Persons with DisabilitiesPhysical ExertionAgedExerciseHumansMobility LimitationWalkingExerciseFatigueFrailtySuccessful aging

Identifiers

PMID33585918
PMCPMC8436976

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.