Evidence map›Paper›PMID 33585518›Full record

ArticleFrontiers in medicine2020

Case Report: Sublingual Microcirculatory Alterations in a Covid-19 Patient With Subcutaneous Emphysema, Venous Thrombosis, and Pneumomediastinum.

Sanjeev Grewal, Brita Harjo, Güclü Aykut, Bülent Ergin, Ralph Nowitzky, Can Ince, Sakir Akin

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sanjeev GrewalDepartment of Intensive Care, Haga Teaching Hospital, The Hague, Netherlands.
Brita HarjoDepartment of Intensive Care, Haga Teaching Hospital, The Hague, Netherlands.
Güclü AykutDepartment of Intensive Care, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands.
Bülent ErginDepartment of Intensive Care, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands.
Ralph NowitzkyDepartment of Intensive Care, Haga Teaching Hospital, The Hague, Netherlands.
Can InceDepartment of Intensive Care, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands.
Sakir AkinDepartment of Intensive Care, Haga Teaching Hospital, The Hague, Netherlands.
Erasmus MC · NLHaga Hospital · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Corona virus disease 2019 (Covid-19) has brought a wide range of challenges in intensive care medicine. Understanding of the pathophysiology of Covid-19 relies on interpreting of its impact on the vascular, particularly microcirculatory system. Herein we report on the first use of the latest generation hand-held vital microscope to evaluate the sublingual microcirculation in a Covid-19 patient with subcutaneous emphysema, venous thrombosis and pneumomediastinum. Remarkably, microcirculatory parameters of the patient were increased during the exacerbation period, which is not a usual finding in critically ill patients mostly presenting with a loss of hemodynamic coherence. In contrast, recovery from the disease led to a subsequent amelioration of these parameters. This report clearly shows the importance of microcirculatory monitoring for evaluating the course and the adequacy of therapy in Covid-19 patients.

Indexed as

COVID-19IDF imagingpneumomediastinumsubcutaneous emphysemasublingual microcirculationvenous thrombosis

Identifiers

PMID33585518
PMCPMC7876339
OpenAlexW3123191875

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.