Evidence map›Paper›PMID 33585437›Full record

ArticleFrontiers in cell and developmental biology2020

Inducing Non-genetically Modified Induced Embryonic Sertoli Cells Derived From Embryonic Stem Cells With Recombinant Protein Factors.

Chenze Xu, Ali Mohsin, Yanxia Luo, Lili Xie, Yan Peng, Qizheng Wang, Waqas Ahmed, Haifeng Hang, Yingping Zhuang, Meijin Guo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Sertoli cells as a hub in testicular development and male reproductive.Frontiers in cell and developmental biology · 2025
    Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Chenze XuState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Ali MohsinState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Yanxia LuoState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Lili XieState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Yan PengState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Qizheng WangState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Waqas AhmedState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Haifeng HangState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Yingping ZhuangState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Meijin GuoState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
East China University of Science and Technology · CNChinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Embryonic Sertoli cells (eSCs) possess multiple supporting functions and research value in gonadal development and sex determination. However, the limitation of acquiring quality eSCs had hindered the further application. Herein, we successfully derived non-genetically modified (non-GM)-induced embryonic Sertoli-like cells (eSLCs) from mouse embryonic stem cells (ESCs) with a TM4 cell-derived conditioned medium containing recombinant endogenous protein factors

Indexed as

embryonic stem cellslentiviral transductionnon-genetically modifiedrecombinant endogenous protein factorsSertoli cells

Identifiers

PMID33585437
PMCPMC7875124
OpenAlexW3125482560

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.