Evidence map›Paper›PMID 33585337›Full record

ArticleEuropean journal of case reports in internal medicine2021

Gitelman Syndrome: A Rare Case of Hypokalaemia and a Novel Mutation.

Clara Matos, Fábio Correia, Inês Nunes da Silva, Sofia Carola, Ana Órfão, Maria Ferreira, Teresa Branco

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of case reports in internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Clara MatosDepartment of Internal Medicine, Hospital Professor Doutor Fernando Fonseca, Amadora, Portugal.
Fábio CorreiaDepartment of Internal Medicine, Hospital Professor Doutor Fernando Fonseca, Amadora, Portugal.
Inês Nunes da SilvaDepartment of Internal Medicine, Hospital Professor Doutor Fernando Fonseca, Amadora, Portugal.
Sofia CarolaDepartment of Internal Medicine, Hospital Professor Doutor Fernando Fonseca, Amadora, Portugal.
Ana ÓrfãoDepartment of Internal Medicine, Hospital Professor Doutor Fernando Fonseca, Amadora, Portugal.
Maria FerreiraDepartment of Internal Medicine, Hospital Professor Doutor Fernando Fonseca, Amadora, Portugal.
Teresa BrancoDepartment of Internal Medicine, Hospital Professor Doutor Fernando Fonseca, Amadora, Portugal.
Hospital Prof. Dr. Fernando Fonseca · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gitelman syndrome (GS) is a hereditary renal tubulopathy caused by mutations in the SLC12A3 gene which encodes the thiazide-sensitive apical sodium-chloride cotransporter. GS is characterized by hypokalaemia, hypomagnesaemia and metabolic alkalosis. Treatment is based on potassium and magnesium replacement LEARNING POINTS: Gitelman syndrome is a rare cause of persistent hypokalaemia.A definitive diagnosis is determined by the identification of mutations in the SLC12A3 gene.Management consists of chronic potassium and magnesium supplementation aimed at symptom control.

Indexed as

Gitelman syndromehereditary renal tubulopathyhypokalaemiaSLC12A3 mutations

Identifiers

PMID33585337
PMCPMC7875576
OpenAlexW3130114833

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.