Evidence map›Paper›PMID 33585190›Full record

ArticleFrontiers in oncology2020

Proteomic Alterations in Multiple Myeloma: A Comprehensive Study Using Bone Marrow Interstitial Fluid and Serum Samples.

Venkatesh Chanukuppa, Ravindra Taware, Khushman Taunk, Tathagat Chatterjee, Sanjeevan Sharma, Venkatesan Somasundaram, Faraz Rashid, Dipankar Malakar, Manas K Santra, Srikanth Rapole

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. A letter to the editor: High prevalence of peripheral neuropathy in multiple myeloma patients and the impact of vitamin D levels, a cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  8. Article
  9. Identification of Ubiquitination-Associated Proteins Using 2D-DIGE.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  10. DIGE Analysis of Immunodepleted Plasma.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  11. DIGE-Based Biomarker Discovery in Blood Cancers.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Clinical Proteomics of Biofluids in Haematological Malignancies.International journal of molecular sciences · 2021
    Review
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Venkatesh ChanukuppaProteomics Lab, National Centre for Cell Science, Pune, India.
Ravindra TawareProteomics Lab, National Centre for Cell Science, Pune, India.
Khushman TaunkProteomics Lab, National Centre for Cell Science, Pune, India.
Tathagat ChatterjeeArmy Hospital (Research and Referral), New Delhi, India.
Sanjeevan SharmaArmed Forces Medical College, Pune, India.
Venkatesan SomasundaramArmed Forces Medical College, Pune, India.
Faraz RashidSciex, Gurgaon, India.
Dipankar MalakarSciex, Gurgaon, India.
Manas K SantraCancer Biology and Epigenetics Lab, National Centre for Cell Science, Pune, India.
Srikanth RapoleProteomics Lab, National Centre for Cell Science, Pune, India.
National Centre for Cell Science · INArmed Forces Medical College · INArmy Hospital Research and Referral · INSavitribai Phule Pune University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple myeloma (MM) is a plasma cell-associated cancer and exists as the second most common hematological malignancy worldwide. Although researchers have been working on MM, a comprehensive quantitative Bone Marrow Interstitial Fluid (BMIF) and serum proteomic analysis from the same patients' samples is not yet reported. The present study involves the investigation of alterations in the BMIF and serum proteome of MM patients compared to controls using multipronged quantitative proteomic approaches

Indexed as

2D-DIGEbone marrow interstitial fluidiTRAQmultiple myelomamultipronged quantitative proteomicsserum biomarkersSWATH-MS

Identifiers

PMID33585190
PMCPMC7879980
OpenAlexW3128129225

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.