ArticleGastroenterology and hepatology from bed to bench2020
Detection and characterization of rotavirus G and P types from children with acute gastroenteritis in Qom, central Iran.
Article in Gastroenterology and hepatology from bed to bench, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Epidemiology and genetic variation of acute viral gastroenteritis in children under five years in the Middle East (2020-2025): a systematic review and meta-analysis.BMC infectious diseases · 2026Pooled it
- Rescue a Reassortant Human-Bovine Rotavirus and a Recombinant NSP3-EGFP Rotavirus Serotype G1.Iranian biomedical journal · 2026Article
- Rotavirus-associated acute gastroenteritis in children under five years: a cross-sectional study from southern Iran.Iranian journal of microbiology · 2026Article
- Evaluation of the detection of diarrhoea-associated RNA viruses in immunocompromised children in Iran.Infection prevention in practice · 2024Article
- Review
- Evaluation of the prevalence of Aeromonas spp., Campylobacter spp., and Clostridioides difficile in immunocompromised children with diarrhea.BMC infectious diseases · 2024Article
- Design of dot-blot hybridization assay for simultaneous detection ofAnnals of medicine and surgery (2012) · 2024Article
- A Clinical Nursing Care Study on the Prevalence of Rotavirus Infection and Acute Diarrhea in Vaccinated Chinese Pediatric Population from 2019-2022.Infection and drug resistance · 2022Article
- Prevalence of enteric adenovirus and co-infection with rotavirus in children under 15 years of age with gastroenteritis in Qom, Iran.Gastroenterology and hepatology from bed to bench · 2022Article
- Biochemical predictors for Sars-Cov-2 severity.Bioinformation · 2021Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThe aim of the study is to estimate the burden of Rotavirus gastroenteritis as well as predominant genotypes of Rotavirus among children less than 5 years of age referring to Pediatric University Hospital in Qom, Iran.
backgroundGastroenteritis is the fourth most common cause of death and accounts for 16% of all deaths in children <5 years of age worldwide.
methodsDuring two years, 130 patients referring to a pediatric hospital were enrolled in this study. After RNA extraction, Rotaviruses were detected by the VP6 gene. Then, G-typing (G1, G2, G3, G4, G8, G9, and G12) and P-typing (P4, P6, and P8) were performed using RT-PCR and specific primers.
resultsThe results of the PCR revealed that from a total of 130 patients, 22 cases (16.9%) showed positive VP6 by RT-PCR. G1 was mostly the predominant serotype (27%), accounting for 22% of all VP7-positive isolates, followed by G9 (18%), G2 (9%), G3 (9%), and G4 (9%). None of the strains revealed the presence of G8 genotype (0%), and 5 specimens (23%) were non-typable. The frequency of P typing was P8 (50%), P6 (23%), P4 (14%), and 3 samples were P-non-typable (13%), respectively. The dominant G-P combination was G1 [8] (32%).
conclusionSuch studies based on typing methods assists in the Rotavirus vaccine introduction by policymakers and design of new effective vaccines.
Indexed as
Identifiers
33585014PMC7881410W3120185453What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.