Evidence map›Paper›PMID 33584958›Full record

ReviewThe Journal of clinical and aesthetic dermatology2020

SARECYCLINE AND THE NARROW-SPECTRUM TETRACYCLINE CONCEPT: Currently Available Data and Potential Clinical Relevance in Dermatology.

James Q Del Rosso

Open access · greenAbstract readReview
In one paragraph

Review in The Journal of clinical and aesthetic dermatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Microorganisms · 2025
    Article
  4. Article
  5. Microbiology spectrum · 2023
    Article
  6. Truncal Acne: An Overview.Journal of clinical medicine · 2022
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

James Q Del RossoDr. Del Rosso is Research Director at JDR Dermatology Research in Las Vegas, Nevada, is with Thomas Dermatology in Las Vegas, Nevada, and is an adjunct clinical professor of dermatology at Touro University Nevada in Henderson, Nevada.
Touro University Nevada · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral tetracyclines are commonly prescribed in dermatology, especially for acne. The most commonly used oral agents for acne treatment over the past several years are doxycycline and minocycline based on their overall efficacy and safety. Available for over five decades as immediate-release formulations, both of these agents exhibit broad-spectrum antibiotic activity and are primarily FDA-approved for treatment of a variety of cutaneous infections. In 2018, oral sarecycline was FDA-approved for the treatment of acne, which is the only disease state for which it was evaluated based on a narrower antibiotic spectrum of activity. This article reviews the overall antibiotic properties of commonly used oral tetracyclines with a focus on explaining the narrow spectrum of activity exhibited by sarecycline. Specifically, sarecycline has high activity against

Indexed as

antibiotic resistancebroad-spectrum antibioticmicrobiomenarrow-spectrum antibioticSarecycline

Identifiers

PMID33584958
PMCPMC7840093
OpenAlexW3132428172

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.