Evidence map›Paper›PMID 33584687›Full record

ArticleFrontiers in immunology2020

Protein Phosphatase PP1 Negatively Regulates IRF3 in Response to GCRV Infection in Grass Carp (

Xudong Hu, Bing Wang, Haohao Feng, Man Zhou, Yusheng Lin, Hong Cao

Abstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xudong HuInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Bing WangInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Haohao FengInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Man ZhouInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Yusheng LinInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Hong CaoInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protein phosphatase-1 (PP1) has an important role in many cell functions, such as cell differentiation, development, immune response and tumorigenesis. However, the specific role of PP1 in the antiviral response in fish remains to be elucidated. In this study, the

Indexed as

Amino Acid SequenceAnimalsCarpsCell NucleusCells, CulturedCytoplasmFish DiseasesFish ProteinsHEK293 CellsHumansInterferon Regulatory Factor-3PhylogenyProtein Phosphatase 1ReoviridaeReoviridae InfectionsUp-RegulationFish ProteinsInterferon Regulatory Factor-3Protein Phosphatase 1antiviralGCRVgrass carpintestinePPP1R3G

Identifiers

PMID33584687
PMCPMC7873974

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.