Evidence map›Paper›PMID 33584664›Full record

ReviewFrontiers in immunology2020

Adipocytes Are the Control Tower That Manages Adipose Tissue Immunity by Regulating Lipid Metabolism.

Jeu Park, Jee Hyung Sohn, Sang Mun Han, Yoon Jeong Park, Jin Young Huh, Sung Sik Choe, Jae Bum Kim

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jeu ParkNational Creative Research Initiatives Center for Adipocyte Structure and Function, Seoul National University, Seoul, South Korea.
Jee Hyung SohnNational Creative Research Initiatives Center for Adipocyte Structure and Function, Seoul National University, Seoul, South Korea.
Sang Mun HanNational Creative Research Initiatives Center for Adipocyte Structure and Function, Seoul National University, Seoul, South Korea.
Yoon Jeong ParkNational Creative Research Initiatives Center for Adipocyte Structure and Function, Seoul National University, Seoul, South Korea.
Jin Young HuhNational Creative Research Initiatives Center for Adipocyte Structure and Function, Seoul National University, Seoul, South Korea.
Sung Sik ChoeNational Creative Research Initiatives Center for Adipocyte Structure and Function, Seoul National University, Seoul, South Korea.
Jae Bum KimNational Creative Research Initiatives Center for Adipocyte Structure and Function, Seoul National University, Seoul, South Korea.
Seoul National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accumulating evidence reveals that adipose tissue is an immunologically active organ that exerts multiple impacts on the regulation of systemic energy metabolism. Adipose tissue immunity is modulated by the interactions between adipocytes and various immune cells. Nevertheless, the underlying mechanisms that control inter-cellular interactions between adipocytes and immune cells in adipose tissue have not been thoroughly elucidated. Recently, it has been demonstrated that adipocytes utilize lipid metabolites as a key mediator to initiate and mediate diverse adipose tissue immune responses. Adipocytes present lipid antigens and secrete lipid metabolites to determine adipose immune tones. In addition, the interactions between adipocytes and adipose immune cells are engaged in the control of adipocyte fate and functions upon metabolic stimuli. In this review, we discuss an integrated view of how adipocytes communicate with adipose immune cells using lipid metabolites. Also, we briefly discuss the newly discovered roles of adipose stem cells in the regulation of adipose tissue immunity.

Indexed as

Lipid MetabolismAdipocytesAdipose TissueAnimalsAntigen PresentationBiomarkersDisease SusceptibilityEnergy MetabolismHumansImmunity, InnateImmunomodulationLipidsNatural Killer T-CellsPanniculitisStem CellsBiomarkersLipidsadipocytesadipose tissue inflammationadipose tissue remodelinginvariant natural killer celllipid metabolite

Identifiers

PMID33584664
PMCPMC7876236
OpenAlexW3127175049

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.