Evidence map›Paper›PMID 33584381›Full record

ArticleFrontiers in psychiatry2021

Children With Disruptive Mood Dysregulation Disorder and Psychopathological Risk in Their Mothers: The Function of Global DNA Methylation.

Valeria Carola, Silvia Cimino, Silvia Bussone, Luca Cerniglia, Renata Tambelli

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Autonomic response and attachment style in disruptive mood dysregulation disorder.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Valeria CarolaDepartment of Dynamic and Clinical Psychology, Sapienza University of Rome, Rome, Italy.
Silvia CiminoDepartment of Dynamic and Clinical Psychology, Sapienza University of Rome, Rome, Italy.
Silvia BussoneDepartment of Dynamic and Clinical Psychology, Sapienza University of Rome, Rome, Italy.
Luca CernigliaFaculty of Psychology, International Telematic University Uninettuno, Rome, Italy.
Renata TambelliDepartment of Dynamic and Clinical Psychology, Sapienza University of Rome, Rome, Italy.
Sapienza University of Rome · ITUniNettuno University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epigenetic mechanisms, in particular DNA methylation, have been implicated in the etiopathogenesis of psychopathologies in adulthood. The significance of this mechanism in child psychopathologies, however, is much less recognized. Here, we examined whether global DNA methylation alteration was associated with the presence of disruptive mood dysregulation disorder (DMDD) in children. Moreover, in light of the relevance of the interplay between children and parents for the onset and maintaining of psychopathology during development, we measured the association between psychological symptoms, attachment styles, and global DNA methylation levels in healthy and DMDD mother-child dyads (mothers:

Indexed as

CBCL/6–18clinical psychologydisruptive mood dysregulation disorderECR-RCepigeneticsglobal DNA methylationsalivaSCL-90-R

Identifiers

PMID33584381
PMCPMC7874238
OpenAlexW3122917476

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.