Evidence map›Paper›PMID 33584179›Full record

ArticleFrontiers in neuroscience2020

Nogo-C Inhibits Peripheral Nerve Regeneration by Regulating Schwann Cell Apoptosis and Dedifferentiation.

Bo Jia, Wei Huang, Yu Wang, Peng Zhang, Zhiwei Wang, Ming Zheng, Tianbing Wang

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in Frontiers in neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Bo JiaTrauma Medicine Center, Peking University People's Hospital, Beijing, China.
Wei HuangTrauma Medicine Center, Peking University People's Hospital, Beijing, China.
Yu WangTrauma Medicine Center, Peking University People's Hospital, Beijing, China.
Peng ZhangTrauma Medicine Center, Peking University People's Hospital, Beijing, China.
Zhiwei WangTrauma Medicine Center, Peking University People's Hospital, Beijing, China.
Ming ZhengDepartment of Physiology and Pathophysiology, Health Science Center, Peking University, Beijing, China.
Tianbing WangTrauma Medicine Center, Peking University People's Hospital, Beijing, China.
Peking University · CNPeking University People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While Nogo protein demonstrably inhibits nerve regeneration in the central nervous system (CNS), its effect on Schwann cells in peripheral nerve repair and regeneration following sciatic nerve injury remains unknown. In this research, We assessed the post-injury expression of Nogo-C in an experimental mouse model of sciatic nerve-crush injury. Nogo-C knockout (Nogo-C

Indexed as

apoptosisdedifferentiationNogo-Cperipheral nerve regenerationSchwann cells

Identifiers

PMID33584179
PMCPMC7873940
OpenAlexW3121617208

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.