ArticleJournal of medical biochemistry2021
The role of oxidative stress in the development of obesity and obesity-related metabolic disorders.
Article in Journal of medical biochemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 130 papers.
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Who cites it
130 citing papers in PubMed, 197 citations in OpenAlex.
- Trial
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- The impact of synbiotic yogurt consumption on insulin-resistance surrogates, atherogenic and novel anthropometric indices in adults with metabolic syndrome: a randomized clinical trial.Nutrition & metabolism · 2026Article
- Cardioprotective effect of spirulina on cafeteria diet-induced cardiac injury in silico and in vivo study.Journal of the science of food and agriculture · 2026Article
- Brown adipose tissue-derived exosomes ameliorate obesity-related hypertension via HuR-mediated restoration of endothelial function.International journal of obesity (2005) · 2026Article
- Altered Lipid and Neurotransmitter Metabolism as Potential Mechanisms of Weight Gain in Women With HIV Initiating INSTIs in a Pilot Study.Journal of acquired immune deficiency syndromes (1999) · 2026Article
- Abdominal Obesity, Hepatic Steatosis, Oxidative Stress and Diastolic Dysfunction in Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease.International journal of molecular sciences · 2026Article
- Obesity, Metabolic Syndrome and MASLD in Children: Inflammation as the Missing Link-A Short Narrative Review.Life (Basel, Switzerland) · 2026Review
- Interplay of Microbiome, Oxidative Stress and Inflammation in Health and Disease.Antioxidants (Basel, Switzerland) · 2026Review
- Subcutaneous and visceral adipose tissue lipidome in children reveals novel lipid species involved in obesity.Journal of physiology and biochemistry · 2026Article
- Elevated maternal pre-transfer serum lipid peroxidation is associated with implantation failure and early pregnancy loss.BMC medicine · 2026Article
- Increased maternal non-esterified fatty acid concentrations during late gestation impair adipose tissue development and metabolic function in Holstein offspring calves.Journal of animal science · 2026Article
- Oxidative stress in adolescents with overweight/obesity.Journal of medical biochemistry · 2026Article
70 more citing papers are in PubMed but not listed here.
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity is a serious medical condition, defined as excessive accumulation of fat. Abdominal fat is recognized as the major risk for obesity related diseases such as: hypertension, dyslipidemia, type 2 diabetes mellitus, coronary heart disease, stroke, non-alcoholic fatty liver disease etc. Fat accumulation is also related to pro-oxidant and pro-inflammatory states. Recently published articles suggest that oxidative stress may be a link between obesity and related complications. Adiposity leads to increased oxidative stress via several multiple biochemical processes such as superoxide generation through the action of NADPH oxidase, glyceraldehyde auto-oxidation, oxidative phosphorylation, protein kinase C (PKC) activation, and polyol and hexosamine pathways. On the other hand, oxidative stress plays a causative role in the development of obesity, by stimulating the deposition of adipose tissue, including preadipocyte proliferation, adipocyte differentiation and growth. Exercise-induced weight loss can improve the redox state by modulating both oxidative stress and antioxidant promoters, which reduce endothelial dysfunction and inflammation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.