Evidence map›Paper›PMID 33584068›Full record

ArticleWorld journal of gastroenterology2021

Could saline irrigation clear all residual common bile duct stones after lithotripsy? A self-controlled prospective cohort study.

Yan-Yan Lin, Yu-Dong Wang, Ping Yue, Xian-Zhuo Zhang, Joseph W Leung, Pan-Pan Jiao, Man Yang, Hai-Ping Wang, Bing Bai, Ying Liu and 4 more

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Intrabiliary ultrasound applied to endoscopic extraction of choledochal stones.Asian biomedicine : research, reviews and news · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Yan-Yan LinDepartment of General Surgery, The First Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China.
Yu-Dong WangDepartment of General Surgery, The First Affiliated Hospital of Henan Polytechnic University, Jiaozuo 454001, Henan Province, China.
Ping YueDepartment of General Surgery, The First Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China.
Xian-Zhuo ZhangDepartment of General Surgery, The First Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China.
Joseph W LeungDepartment of Gastroenterology, Sacramento VA Medical Center, Mather, CA 95655-4200, United States.
Pan-Pan JiaoThe First School of Clinical Medicine, Lanzhou University, Lanzhou 730000, Gansu Province, China.
Man YangDepartment of Gastroenterology, Songgang People's Hospital, Shenzhen 518105, Guangdong Province, China.
Hai-Ping WangClinical Medical College Cancer Center of Lanzhou University, The First Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China.
Bing BaiDepartment of General Surgery, The First Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China.
Ying LiuSchool of Foreign Languages and Literatures, Lanzhou University, Lanzhou 730000, Gansu Province, China.
Jin-Duo ZhangDepartment of General Surgery, The First Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China.
Hong-Bo ChenSchool of Pharmaceutical Sciences, Sun Yat-sen University, Shenzhen 518105, Guangdong Province, China.
Wen-Bo MengDepartment of General Surgery, The First Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China.
Xun LiDepartment of General Surgery, The First Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China.
First Hospital of Lanzhou University · CNLanzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA previous study showed that irrigation with 100 mL saline reduced residual common bile duct (CBD) stones, which potentially cause recurrent stones after endoscopic retrograde cholangiopancreatography.

aimTo determine whether saline irrigation can improve CBD clearance after lithotripsy.

methodsThis prospective self-controlled study enrolled patients receiving mechanical lithotripsy for large (> 1.2 cm) CBD stones. After occlusion cholangiography confirmed CBD stone clearance, peroral cholangioscopy (POC) was performed to determine clearance scores based on the number of residual stones. The amounts of residual stones spotted

resultsBetween October 2018 and January 2020, 47 patients had CBD clearance scores of 2.4 ± 1.1 without saline irrigation, 3.5 ± 0.7 with 50 mL irrigation, and 4.6 ± 0.6 with 100 mL irrigation (

conclusionIrrigation with 100 mL of saline may not clear all residual CBD stones after lithotripsy, especially in patients with PAD and/or a dilated (> 15 mm) CBD. Pigment residual stones are soft and commonly found in patients with PAD. Additional saline irrigation may be required to remove retained stones.

Indexed as

GallstonesLithotripsyCholangiopancreatography, Endoscopic RetrogradeCommon Bile DuctHumansProspective StudiesCommon bile duct gall stonesEndoscopic retrograde cholangiopancreatographyPeriampullary diverticulaPeroral cholangioscopyProspective cohort studySaline irrigation

Identifiers

PMID33584068
PMCPMC7852583
OpenAlexW3122021950

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.