Evidence map›Paper›PMID 33583576›Full record

ReviewClinical therapeutics2021

Sex- or Gender-specific Differences in the Clinical Presentation, Outcome, and Treatment of SARS-CoV-2.

Jeannette Wolfe, Basmah Safdar, Tracy E Madsen, Kinjal N Sethuraman, Bruce Becker, Marna Rayl Greenberg, Alyson J McGregor

Abstract readReview
In one paragraph

Review in Clinical therapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jeannette WolfeDepartment of Emergency Medicine, University of Massachusetts Medical School-Baystate, Springfield, MA, USA. Electronic address: Jeannette.Wolfe@baystatehealth.org.
Basmah SafdarDepartment of Emergency Medicine, Yale University School of Medicine, New Haven, CT, USA.
Tracy E MadsenDepartment of Emergency Medicine, Warren Alpert Medical School, Brown University, Providence, RI, USA.
Kinjal N SethuramanDepartment of Emergency Medicine, School of Medicine, University of Maryland, Baltimore, MD, USA.
Bruce BeckerDepartment of Emergency Medicine, Warren Alpert Medical School, Brown University, Providence, RI, USA.
Marna Rayl GreenbergDepartment of Emergency and Hospital Medicine, Lehigh Valley Health Network/Morsani College of Medicine, University of South Florida, Allentown, PA, USA.
Alyson J McGregorDepartment of Emergency Medicine, Warren Alpert Medical School, Brown University, Providence, RI, USA.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

This review describes the sex and gender differences in COVID-19 presentation, treatment, and outcomes. We discuss the differences between the sexes in susceptibility to infection, the role of sex chromosomes on the body's immunologic response and the influence of hormones on the body's response to the virus. Additionally, the sex differences in clinical and laboratory presentation, complications of infection and outcomes, as well as differences in response to treatment and prevention are reviewed.

Indexed as

COVID-19FemaleHumansMaleSARS-CoV-2Sex FactorsImmunologylong haulersSars Cov2sex and gender based medicinesex-disaggregated analysis

Identifiers

PMID33583576
PMCPMC7833665

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.