ReviewPsychological medicine2021
Genetics of eating disorders in the genome-wide era.
Review in Psychological medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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Who cites it
24 citing papers in PubMed.
- Shared and distinct genetic architectures of eating disorders and obesity: From monogenic causes to polygenic risk.Reviews in endocrine & metabolic disorders · 2026Review
- Investigating Relationships Between Genetic Risk, Childhood Maltreatment, and Eating Disorders in Women.Biological psychiatry global open science · 2026Article
- Anorexia nervosa: 150 years of critical theory.Journal of eating disorders · 2026Review
- Predicting adolescent disordered eating and behaviours: exploring environmental moderators of polygenic risk.Journal of child psychology and psychiatry, and allied disciplines · 2025Article
- "I thought if my parents got involved, then they'd make me get better": emerging adults' experiences of support from family and friends during anorexia nervosa.Journal of eating disorders · 2025Article
- Genomic links between symptoms of eating disorders and suicidal ideation.European psychiatry : the journal of the Association of European Psychiatrists · 2025Article
- Early intervention in eating disorders: introducing the chronopathogram.Eating and weight disorders : EWD · 2025Review
- Article
- Exploring the self-perceived causes of eating disorders among Chinese social media users with self-reported eating disorders.Journal of eating disorders · 2024Article
- Anorexia nervosa in children and adolescents: an early detection of risk factors.Italian journal of pediatrics · 2024Article
- Parental styles are associated with eating disorder symptoms, anxiety, interpersonal difficulties, and nucleus accumbens response.Eating and weight disorders : EWD · 2024Article
- Maternal perspectives on the intergenerational transmission of eating disorders.Journal of eating disorders · 2024Article
- Eating Disorders: Updates and Innovations.Focus (American Psychiatric Publishing) · 2024Article
- Interplay of polygenic liability with birth-related, somatic, and psychosocial factors in anorexia nervosa risk: a nationwide study.Psychological medicine · 2024Article
- Building Confidence in Discussing Genetics With Patients With Eating Disorders and Their Families.Focus (American Psychiatric Publishing) · 2024Article
- The Nepean Belief Scale (NBS) as a tool to investigate the intensity of beliefs in anorexia nervosa: psychometric properties of the Italian version.Eating and weight disorders : EWD · 2023Article
- Behavioural susceptibility theory: the role of appetite in genetic susceptibility to obesity in early life.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Review
- Risk factors for anorexia nervosa: A population-based investigation of sex differences in polygenic risk and early life exposures.The International journal of eating disorders · 2023Article
- "I think it is woven through me, and sadly that means it is woven through our family life": the experiences and support needs of mothers with eating disorders.Journal of eating disorders · 2023Article
- My Diet Study: protocol for a two-part observational, longitudinal, psycho-biological study of dieting in Australian youth.Frontiers in public health · 2023Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Enabled by advances in high throughput genomic sequencing and an unprecedented level of global data sharing, molecular genetic research is beginning to unlock the biological basis of eating disorders. This invited review provides an overview of genetic discoveries in eating disorders in the genome-wide era. To date, five genome-wide association studies on eating disorders have been conducted - all on anorexia nervosa (AN). For AN, several risk loci have been detected, and ~11-17% of the heritability has been accounted for by common genetic variants. There is extensive genetic overlap between AN and psychological traits, especially obsessive-compulsive disorder, and intriguingly, with metabolic phenotypes even after adjusting for body mass index (BMI) risk variants. Furthermore, genetic risk variants predisposing to lower BMI may be causal risk factors for AN. Causal genes and biological pathways of eating disorders have yet to be elucidated and will require greater sample sizes and statistical power, and functional follow-up studies. Several studies are underway to recruit individuals with bulimia nervosa and binge-eating disorder to enable further genome-wide studies. Data collections and research labs focused on the genetics of eating disorders have joined together in a global effort with the Psychiatric Genomics Consortium. Molecular genetics research in the genome-wide era is improving knowledge about the biology behind the established heritability of eating disorders. This has the potential to offer new hope for understanding eating disorder etiology and for overcoming the therapeutic challenges that confront the eating disorder field.
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