ArticleBMC musculoskeletal disorders2021
Muscle activity and acute stress in fibromyalgia.
Article in BMC musculoskeletal disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Metaboliset Muutokset ja Lihastoiminta Fibromyalgiassa
Ultrasound-imaged Muscle Architecture and Muscle Strength in Fibromyalgia and it's Correlation With Pain, Disease Activity, and Functionality
Who cites it
18 citing papers in PubMed, 27 citations in OpenAlex.
- Cardiac output and arteriovenous oxygen difference contribute to lower peak oxygen uptake in patients with fibromyalgia.BMC musculoskeletal disorders · 2023Trial
- Trial
- Reduced lumbar myofascial mobility in chronic low back pain quantified using MR elastography-based slip interface imaging.European radiology experimental · 2026Article
- Changes in the mechanical properties and pressure pain thresholds of muscles in patients with fibromyalgia and their relationship with clinical parameters: a case-control study.European journal of applied physiology · 2026Article
- A systematic scoping review and conceptual analysis of new-onset fibromyalgia manifestations after non-hospitalized COVID-19: empirics, definitions, methodologies, pathophysiology, mapping of literature, and knowledge gaps.Journal of translational medicine · 2026Article
- Muscle and cerebral oxygenation during exercise in fibromyalgia: a near-infrared spectroscopy study.European journal of applied physiology · 2026Article
- Abnormal Resting-State Functional Connectivity Between the Dorsal Anterior Cingulate Cortex and the Limbic System Contributes to Pain and Emotion Regulation Impairment in Fibromyalgia Patients.International journal of rheumatic diseases · 2026Article
- Personality Assessment Inventory in Fibromyalgia: Links to Functional, Physical-Somatic, and Emotional Impact.European journal of investigation in health, psychology and education · 2025Article
- Diagnostic utility of deep tendon reflex responses in rectus femoris and triceps brachii in fibromyalgia: a clinical and electrophysiological study.Rheumatology international · 2025Article
- Machine learning identifies fatigue as a key symptom of fibromyalgia reflected in tyrosine, purine, pyrimidine, and glutaminergic metabolism.Clinical and translational science · 2024Article
- Transcutaneous auricular vagus nerve stimulation modulates masseter muscle activity, pain perception, and anxiety levels in university students: a double-blind, randomized, controlled clinical trial.Frontiers in integrative neuroscience · 2024Article
- Mediation Effect of Kinesiophobia on the Relationship between Cervical Joint Position Sense and Limits of Stability in Individuals with Fibromyalgia Syndrome: A Cross-Sectional Study Using Mediation Analysis.Journal of clinical medicine · 2023Article
- Heart rate variability responses to cognitive stress in fibromyalgia are characterised by inadequate autonomous system stress responses: a clinical trial.Scientific reports · 2023Article
- Evaluation of Physiotherapy Impact on Neuromuscular Tension in Analog Astronauts at the LunAres Habitat.International journal of environmental research and public health · 2022Article
- Cervical Spondylosis as a Hidden Contributing Factor to Fibromyalgia: A Case Report.International medical case reports journal · 2022Article
- Elevated highly sensitive C-reactive protein in fibromyalgia associates with symptom severity.Rheumatology advances in practice · 2022Article
- The Relationship between Stress and Masticatory Muscle Activity in Female Students.Journal of clinical medicine · 2021Article
- Pain-sensorimotor interactions: New perspectives and a new model.Neurobiology of pain (Cambridge, Mass.)Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundFibromyalgia (FM) patients are likely to differ from healthy controls in muscle activity and in reactivity to experimental stress.
methodsWe compared psychophysiological reactivity to cognitive stress between 51 female FM patients aged 18 to 65 years and 31 age- and sex-matched healthy controls. They underwent a 20-minute protocol consisting of three phases of relaxation and two phases of cognitive stress. We recorded surface electromyography normalized to maximum voluntary muscle contraction (%EMG), the percentage of time with no muscle activity (EMG rest time), and subjective pain and stress intensities. We compared group reactivity using linear modelling and adjusted for psychological and life-style factors.
resultsThe FM patients had a significantly higher mean %EMG (2.2 % vs. 1.0 %, p < 0.001), pain intensity (3.6 vs. 0.2, p < 0.001), and perceived stress (3.5 vs. 1.4, p < 0.001) and lower mean EMG rest time (26.7 % vs. 47.2 %, p < 0.001). In the FM patients, compared with controls, the pain intensity increased more during the second stress phase (0.71, p = 0.028), and the %EMG decreased more during the final relaxation phase (-0.29, p = 0.036). Within the FM patients, higher BMI predicted higher %EMG but lower stress. Leisure time physical activity predicted lower %EMG and stress and higher EMG rest time. Higher perceived stress predicted lower EMG rest time, and higher trait anxiety predicted higher pain and stress overall.
conclusionsOur results suggest that repeated cognitive stress increases pain intensity in FM patients. FM patients also had higher resting muscle activity, but their muscle activity did not increase with pain. Management of stress and anxiety might help control FM flare-ups.
trial registrationRetrospectively registered on ClinicalTrials.gov ( NCT03300635 ).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.