ArticleCirculation. Cardiovascular imaging2021
Hemodynamics and Clinical Implications of Occult Left Ventricular Dysfunction in Adults Undergoing Ebstein Anomaly Repair.
Article in Circulation. Cardiovascular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 14 citations in OpenAlex.
- Association Between HIV Infection Duration and Left Ventricular Concentric Remodeling and Myocardial Fibrosis: A Cross-Sectional Study Using Cardiac MRI.Journal of magnetic resonance imaging : JMRI · 2026Article
- Prognostic Implication of Heart Failure With Reduced and Midrange Ejection Fraction in Adults With Congenital Heart Disease.CJC pediatric and congenital heart disease · 2026Article
- Role of strain imaging for risk stratification in Fontan patients with normal ventricular ejection fraction.European heart journal. Cardiovascular Imaging · 2025Article
- The mechanics of congenital heart disease: from a morphological trait to the functional echocardiographic evaluation.Frontiers in cardiovascular medicine · 2024Review
- Prognostic implications of atrial fibrillation in adults with Ebstein anomaly.Heart (British Cardiac Society) · 2023Article
- Incidence and Outcomes of Advanced Heart Failure in Adults With Congenital Heart Disease.Circulation. Heart failure · 2022Article
- Role of Echocardiography for Assessment of Cardiac Remodeling in Congenitally Corrected Transposition of Great Arteries.Circulation. Cardiovascular imaging · 2022Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundLeft ventricular global longitudinal strain (LVGLS) can detect early phases of LV systolic dysfunction, but its application has not been studied in Ebstein anomaly. We hypothesized that LVGLS can detect early phases of LV systolic dysfunction and that patients with occult LV systolic dysfunction will have worse hemodynamics, end-organ dysfunction, and suboptimal postoperative LV reverse remodeling after tricuspid valve surgery in comparison to patients with normal LV systolic function.
methodsIn this retrospective cohort study, 371 Ebstein patients that underwent tricuspid valve surgery were divided into 3 groups: normal LV systolic function (normal LVGLS and LV ejection fraction; n=244, 77%), occult LV systolic dysfunction (abnormal LVGLS with normal LV ejection fraction; n=44, 14%), and overt LV systolic dysfunction (abnormal LVGLS and LV ejection fraction; n=27, 9%).
resultsCompared with the normal LV function group, the occult group had smaller LV volume and cardiac output (2.1±0.4 versus 2.9±0.6 L/min per m
conclusionsAbnormal LVGLS was associated with suboptimal postoperative LV reverse remodeling. These data suggest that LVGLS can potentially be used for risk stratification and provides a foundation for further studies to determine whether optimal heart failure therapy or tricuspid valve intervention can improve outcomes for LV systolic dysfunction in patients with Ebstein anomaly.
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