Evidence map›Paper›PMID 33583183›Full record

ArticleACS applied materials & interfaces2021

Metal Nanoparticles/MoS

Engin Er, Ana Sánchez-Iglesias, Alessandro Silvestri, Blanca Arnaiz, Luis M Liz-Marzán, Maurizio Prato, Alejandro Criado

Open access · greenAbstract read
In one paragraph

Article in ACS applied materials & interfaces, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 83 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. SERS Immunosensors for Cancer Markers Detection.Materials (Basel, Switzerland) · 2023
    Review
  11. Article
  12. MoSNanomaterials (Basel, Switzerland) · 2023
    Article
  13. Article
  14. Article
  15. Recent Advances in Sandwich SERS Immunosensors for Cancer Detection.International journal of molecular sciences · 2022
    Review
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Engin ErCenter for Cooperative Research in Biomaterials (CIC BiomaGUNE), Basque Research and Technology Alliance (BRTA), 20014 Donostia-San Sebastián, Spain.
Ana Sánchez-IglesiasCenter for Cooperative Research in Biomaterials (CIC BiomaGUNE), Basque Research and Technology Alliance (BRTA), 20014 Donostia-San Sebastián, Spain.ORCID http://orcid.org/0000-0003-1871-8742
Alessandro SilvestriCenter for Cooperative Research in Biomaterials (CIC BiomaGUNE), Basque Research and Technology Alliance (BRTA), 20014 Donostia-San Sebastián, Spain.
Blanca ArnaizCenter for Cooperative Research in Biomaterials (CIC BiomaGUNE), Basque Research and Technology Alliance (BRTA), 20014 Donostia-San Sebastián, Spain.ORCID http://orcid.org/0000-0001-5789-0321
Luis M Liz-MarzánCenter for Cooperative Research in Biomaterials (CIC BiomaGUNE), Basque Research and Technology Alliance (BRTA), 20014 Donostia-San Sebastián, Spain.ORCID http://orcid.org/0000-0002-6647-1353
Maurizio PratoCenter for Cooperative Research in Biomaterials (CIC BiomaGUNE), Basque Research and Technology Alliance (BRTA), 20014 Donostia-San Sebastián, Spain.ORCID http://orcid.org/0000-0002-8869-8612
Alejandro CriadoCenter for Cooperative Research in Biomaterials (CIC BiomaGUNE), Basque Research and Technology Alliance (BRTA), 20014 Donostia-San Sebastián, Spain.ORCID http://orcid.org/0000-0002-9732-513X
CIC biomaGUNE · ESIkerbasque · ESAnkara University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The detection of cancer biomarkers at an early stage of tumor development is vital for effective diagnosis and treatment of cancer. Current diagnostic tools can often detect cancer only when the biomarker levels are already too high, so that the tumors have spread and treatments are less effective. It is urgent therefore to develop highly sensitive assays for the detection of such biomarkers at the lowest possible concentration. In this context, we developed a sandwich immunoassay based on surface-enhanced Raman scattering (SERS) for the ultrasensitive detection of α-fetoprotein (AFP), which is typically present in human serum as a biomarker indicative of early stages of hepatocellular carcinoma. In the immunoassay design, molybdenum disulfide (MoS

Indexed as

Immunoassayalpha-FetoproteinsDisulfidesGoldHumansMetal NanoparticlesMolybdenumParticle SizeSilverSpectrum Analysis, RamanSurface PropertiesAFP protein, humanalpha-FetoproteinsDisulfidesGoldMolybdenummolybdenum disulfideSilverAu−Ag core−shell nanostructuresimmunosensormolybdenum disulfidesurface-enhanced Raman scattering (SERS)α-fetoprotein

Identifiers

PMID33583183
PMCPMC7908013
OpenAlexW3130698428

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.