Evidence map›Paper›PMID 33582977›Full record

ArticleDermatology and therapy2021

The Role of Photoprotection in Optimizing the Treatment of Atopic Dermatitis.

Jaime Piquero-Casals, José Manuel Carrascosa, Daniel Morgado-Carrasco, Mridvika Narda, Carles Trullas, Corinne Granger, Gabriella Fabbrocini

Open access · goldAbstract read
In one paragraph

Article in Dermatology and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. The Promising Role of Polyphenols in Skin Disorders.Molecules (Basel, Switzerland) · 2024
    Review
  5. The immunomodulatory activity ofJournal of Taibah University Medical Sciences · 2024
    Article
  6. Observational
  7. Review
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Jaime Piquero-CasalsDermik, Multidisciplinary Dermatology Clinic, Barcelona, Spain. j.piquero@dermik.es.ORCID http://orcid.org/0000-0002-4481-5602
José Manuel CarrascosaDepartment of Dermatology, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma of Barcelona, IGTP, Badalona, Spain.
Daniel Morgado-CarrascoDepartment of Dermatology, Hospital Clínic de Barcelona, Universitat de Barcelona, Barcelona, Spain.
Mridvika NardaInnovation and Development, ISDIN, Barcelona, Spain.
Carles TrullasInnovation and Development, ISDIN, Barcelona, Spain.
Corinne GrangerInnovation and Development, ISDIN, Barcelona, Spain.
Gabriella FabbrociniDepartment of Clinical Medicine and Surgery, University of Naples Federico II, Napoli, Italy.
Isdin (Spain) · ESHospital Clínic de Barcelona · ESHospital Universitari Germans Trias i Pujol · ESUniversity Dermatology · USUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atopic dermatitis (AD) is a chronic inflammatory skin disease with an estimated prevalence of 10-15% in children and 2-10% in adults. Clinically, there is notable phenotypic variability driven by a complex interaction between genetics, immune function, and the environment. Impairment of the skin barrier plays a significant role in the pathogenesis of AD. The apparent beneficial effect of sunlight in patients with atopic eczema is questioned due to its capacity to disrupt the skin barrier and generate free radicals that can damage proteins, lipids, and DNA. The sum of the external factors that an individual is exposed to throughout their lifetime is termed the exposome. Environmental factors such as sun exposure, temperature, and humidity contribute to both AD flares and regional prevalence variation. Literature on photoprotection in atopic dermatitis is very scarce. The use of adequate sunscreens in atopic dermatitis can ensure the level of photoprotection required to prevent skin photoaging and skin cancer and to mitigate skin barrier dysfunction, decrease inflammation, and neutralize facial redness. Herein we discuss and review the role of UV radiation and the exposome in the etiology of AD, as well as the role of adequate photoprotection.

Indexed as

Atopic dermatitisEczemaExposomeNonpharmacologicPhotoprotectionSkin barrierSunscreensUltraviolet radiation

Identifiers

PMID33582977
PMCPMC8019014
OpenAlexW3132843216

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.