ReviewCurrent hypertension reports2021
Autonomic Cardiovascular Alterations in Chronic Kidney Disease: Effects of Dialysis, Kidney Transplantation, and Renal Denervation.
Review in Current hypertension reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 38 citations in OpenAlex.
- Tubulointerstitial inflammation in glomerular diseases: mechanistic pathways, prognostic value, and translational therapeutic targets.Renal failure · 2026Review
- Post-transplant atrial tachyarrhythmias: Epidemiology, mechanisms, outcomes, and management across solid organs.World journal of transplantation · 2026Review
- Metabolic disorder-MASLD-cardiovascular disease-kidney disease (MMCK) syndrome: an expansion of the Cardiovascular-Kidney-Metabolic (CKM) framework.Cardiovascular diabetology. Endocrinology reports · 2026Review
- Higher cardiovascular risk observed with beta-blockers in CKD patients without prior cardiovascular disease.Clinical kidney journal · 2026Article
- Post-exercise heart rate recovery across stages of non-dialysis chronic kidney disease.Journal of human hypertension · 2026Observational
- Article
- Autonomic-vascular dysregulation in CKD-associated hypertension: a narrative review with evidence hierarchy.Frontiers in neuroscience · 2026Review
- Mortality prediction in hemodialysis patients using heart rate variability and skin sympathetic nerve activity.Renal failure · 2025Article
- Is It Time to Abandon the Kidney-Centered View on the Origin of Primary Hypertension?Hypertension (Dallas, Tex. : 1979) · 2025Review
- Renal denervation in dialysis patients: long-term outcomes in a real-world setting.Clinical kidney journal · 2025Article
- The autonomic nervous system and bone health in chronic kidney disease.European journal of clinical investigation · 2025Review
- Renalase, dopamine, and norepinephrine as markers for the development of hypertension in CKD patients.BMC nephrology · 2025Article
- Multi-Organ Denervation: The Past, Present and Future.Journal of clinical medicine · 2025Review
- Autonomic Nervous System Dysregulation and Bone Health in Patients with CKD: Potential for Intervention.Clinical journal of the American Society of Nephrology : CJASN · 2025Article
- Autonomic Dysfunction and Inflammation in CKD: A High-Risk Pathway.Journal of the American Society of Nephrology : JASN · 2025Article
- Association between the age-adjusted Charlson Comorbidity Index and complications after kidney transplantation: a retrospective observational cohort study.BMC nephrology · 2024Observational
- Non-invasive approaches to hydration assessment: a literature review.Urolithiasis · 2024Review
- The Clinical Significance and Application of Heart Rate Variability in Dialysis Patients: A Narrative Review.Biomedicines · 2024Review
- Article
- Diagnostic accuracy of Bellavere's score in cardiac autonomic neuropathy among chronic kidney disease patients: a study of prevalence and dialysis impact.Frontiers in medicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewTo review the results of studies of the effects of dialysis and kidney transplantation on the autonomic nervous system alterations that occur in chronic kidney disease. RECENT
findingsVagal control of the heart mediated by arterial baroreceptors is altered early in the course of the renal disease. Sympathetic activation occurs, with increases in resting heart rate, venous plasma norepinephrine levels, muscle sympathetic nerve traffic, and other indirect indices of adrenergic drive. The magnitude of the changes reflects the clinical severity of the kidney disease. Both the sympathetic and parasympathetic alterations have a reflex origin, depending on the impairment in baroreflex and cardiopulmonary reflex control of the cardiovascular system. These alterations are partially reversed during acute hemodialysis, but the responses are variable depending on the specific type of dialytic treatment that is employed. Renal transplantation improves reflex cardiovascular control, resulting in sympathoinhibition following renal transplantation if the native kidneys are removed. Sympathoinhibitory effects have been also reported in renal failure patients after bilateral renal denervation. Assessment of autonomic nervous system responses to dialysis and renal transplantation provides information of clinical interest, given the evidence that autonomic alterations are involved in the development and progression of cardiovascular complications, as well as in the prognosis of chronic kidney disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.