Evidence map›Paper›PMID 33582889›Full record

ArticleAIDS and behavior2021

Overcoming Ethical Challenges to Engaging Men Who Have Sex with Women in HIV Research.

Hussain A Zaidi, Mxolisi Mathenjwa, Nzwakie Mosery, Kasey O'Neil, Pooja Chitneni, Christina Psaros, Hazar Khidir, Steven A Safren, David R Bangsberg, Sadath A Sayeed and 2 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AIDS and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 2 countries.

Hussain A ZaidiDivision of Infectious Disease, University of Alabama at Birmingham, 212 Zeigler Research Building, 1720 2nd Avenue South, Birmingham, AL, 35294, USA.
Mxolisi MathenjwaMatCH Research Unit (MRU), Department of Obstetrics and Gynaecology, University of the Witwatersrand, Durban, KwaZulu-Natal, South Africa.
Nzwakie MoseryMatCH Research Unit (MRU), Department of Obstetrics and Gynaecology, University of the Witwatersrand, Durban, KwaZulu-Natal, South Africa.
Kasey O'NeilDivision of Infectious Disease, University of Alabama at Birmingham, 212 Zeigler Research Building, 1720 2nd Avenue South, Birmingham, AL, 35294, USA.
Pooja ChitneniDepartment of Internal Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Christina PsarosHarvard Medical School, Boston, MA, USA.
Hazar KhidirHarvard Medical School, Boston, MA, USA.
Steven A SafrenDepartment of Psychology, University of Miami, Miami, FL, USA.
David R BangsbergHarvard Medical School, Boston, MA, USA.
Sadath A SayeedDepartment of Global Health and Social Medicine, Harvard Medical School, Boston, MA, USA.
Jennifer A SmitMatCH Research Unit (MRU), Department of Obstetrics and Gynaecology, University of the Witwatersrand, Durban, KwaZulu-Natal, South Africa.
Lynn T MatthewsDivision of Infectious Disease, University of Alabama at Birmingham, 212 Zeigler Research Building, 1720 2nd Avenue South, Birmingham, AL, 35294, USA. lynnmatthews@uabmc.edu.ORCID http://orcid.org/0000-0001-6167-6328
Harvard University · USUniversity of the Witwatersrand · ZAUniversity of Alabama at Birmingham · USBoston Children's Hospital · USBrigham and Women's Hospital · USSwarthmore College · USUniversity of Miami · US

Funding

The University of Miami AIDS Research Center on Mental Health and HIV/AIDS - Center for HIV & Research in Mental Health (CHARM)Research Core & MHD-CEP30MH133399 · NIMH · UNIVERSITY OF MIAMI CORAL GABLES · PI Steven A Safren · 2023 to 2026
$8.9M
University of Miami Developmental HIV/AIDS Mental Health Research Center (D-ARC)P30MH116867 · NIMH · UNIVERSITY OF MIAMI CORAL GABLES · PI SAFREN, STEVEN A · 2019 to 2023
$6.5M
Addressing psychosocial comorbidities in HIV treatment and preventionK24DA040489 · NIDA · UNIVERSITY OF MIAMI CORAL GABLES · PI SAFREN, STEVEN A · 2016 to 2020
$931k
ART-based safer conception for HIV+ South African men who want to have childrenR34MH100948 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI MATTHEWS, LYNN T · 2014 to 2016
$521k
NIDA NIH HHS K24 DA040489NIMH NIH HHS P30 MH116867NIMH NIH HHS P30 MH133399NIMH NIH HHS R34 MH100948NIMH NIH HHS R34MH100948
6 · The paper itself

Abstract

Men who have sex with women are understudied in HIV research despite the extent to which they experience HIV-related mortality and contribute to the epidemic among women. During our experience of developing and piloting an HIV prevention intervention for men living with HIV in South Africa, and planning to have a child with an HIV-negative woman, ethical questions were posed regarding implementation of a male-centered intervention that did not require female partner participation. Two overarching ethical issues were the potential for (1) compromising women's reproductive and sexual autonomy and (2) increasing HIV-acquisition risks for the woman because the intervention efficacy was unknown. We describe here how these concerns were addressed to facilitate development of a male-centered HIV-prevention intervention. We hope this process manuscript will support researchers, clinicians, and reviewers to engage men who have sex with women in HIV prevention and care.

Indexed as

Acquired Immunodeficiency SyndromeHIV InfectionsSexual BehaviorFamily Planning ServicesFemaleHumansMaleSouth AfricaCouplesEngaging menEthicsHIVReproductive health

Identifiers

PMID33582889
PMCPMC10698834
OpenAlexW3133470472

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.