ArticleJournal of affective disorders2021
Evaluating the timing of differences in activity related to depression symptoms across adulthood in the United States.
Article in Journal of affective disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Circadian Influences on the Habenula and Their Potential Contribution to Neuropsychiatric Disorders.Frontiers in behavioral neuroscience · 2021Pooled it
- Association of improvement and worsening of depressive symptoms with arthritis.BMC geriatrics · 2024Article
- Twenty-four-hour physical activity patterns associated with depressive symptoms: a cross-sectional study using big data-machine learning approach.BMC public health · 2024Article
- Waking up on the wrong side of the bed: Depression severity moderates daily associations between sleep duration and morning affect.Journal of sleep research · 2024Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
backgroundRelative activity deficits found in people with (verses without) depression symptoms/disorders may accumulate uniformly throughout the day, or they may tend to be expressed at specific times. Evidence for the latter would suggest times when behavioral approaches are most needed to reduce depression and its health consequences.
methodsWe performed a secondary-data analysis of participants who contributed valid accelerometer data at the 2005-2006 National Health and Nutrition Examination Survey (n=4390). Participants were categorized according to the Patient Health Questionnaire-9 standard cut-point of ≥10 (i.e., people with versus without clinically significant depression symptoms). Average levels of accelerometer-measured activity in two-hour bins were the dependent variable in mixed models testing if the relationship between depression status and activity level differed by time of day; and if any such relations varied by age group (18-29 years, 30-44 years, 45-59 years, and 60+ years).
resultsIn adults over the age of 30, people with depression symptoms had generally lower levels of activity across the day, but these effects were most markedly pronounced in the morning hours. We found no differences in activity levels associated with prevalent depression symptoms among people 18-30 years of age. LIMITATIONS: Core aspects of depression pathophysiology that produce these different activity patterns and confer their effects on mood were not measured.
conclusionsIn adults 30 years and older, efforts to ameliorate relative activity deficits associated with depression may benefit from considering the apparently outsized role of inactivity that occurs in the morning.
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