Evidence map›Paper›PMID 33582388›Full record

ArticleEuropean journal of medicinal chemistry2021

New dual 5-HT1A and 5-HT7 receptor ligands derived from SYA16263.

Edward Ofori, Edem K Onyameh, Uma M Gonela, Chandrashekhar Voshavar, Barbara Bricker, Tracy L Swanson, Amy J Eshleman, Jennifer L Schmachtenberg, Shelley H Bloom, Aaron J Janowsky and 1 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of medicinal chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Copper(II)-Catalyzed Selective CFrontiers in chemistry · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Edward OforiDivision of Basic Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Institute of Public Health, Florida A&M University, Tallahassee, FL, 32307, USA.
Edem K OnyamehDivision of Basic Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Institute of Public Health, Florida A&M University, Tallahassee, FL, 32307, USA.
Uma M GonelaDivision of Basic Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Institute of Public Health, Florida A&M University, Tallahassee, FL, 32307, USA.
Chandrashekhar VoshavarDivision of Basic Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Institute of Public Health, Florida A&M University, Tallahassee, FL, 32307, USA.
Barbara BrickerDivision of Basic Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Institute of Public Health, Florida A&M University, Tallahassee, FL, 32307, USA.
Tracy L SwansonResearch Service, VA Portland Health Care System, And Department of Psychiatry, Oregon Health and Science University, Portland, OR, 97239, USA.
Amy J EshlemanResearch Service, VA Portland Health Care System, And Department of Psychiatry, Oregon Health and Science University, Portland, OR, 97239, USA.
Jennifer L SchmachtenbergResearch Service, VA Portland Health Care System, And Department of Psychiatry, Oregon Health and Science University, Portland, OR, 97239, USA.
Shelley H BloomResearch Service, VA Portland Health Care System, And Department of Psychiatry, Oregon Health and Science University, Portland, OR, 97239, USA.
Aaron J JanowskyResearch Service, VA Portland Health Care System, And Department of Psychiatry, Oregon Health and Science University, Portland, OR, 97239, USA.
Seth Y AblordeppeyDivision of Basic Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Institute of Public Health, Florida A&M University, Tallahassee, FL, 32307, USA. Electronic address: seth.ablordeppey@famu.edu.
Florida Agricultural and Mechanical University · USOregon Health & Science University · US

Funding

Research Project-3: Effectiveness of an eHealth intervention for uptake of cervical cancer screening in Hispanic womenU54MD007582 · NIMHD · FLORIDA AGRICULTURAL AND MECHANICAL UNIV · PI Eunsook Yu Lee · 2019 to 2026
$28.1M
A New Approach for the Development of Novel Antipsychotic DrugsSC1GM116724 · NIGMS · FLORIDA AGRICULTURAL AND MECHANICAL UNIV · PI ABLORDEPPEY, SETH Y · 2016 to 2019
$1.4M
NIGMS NIH HHS SC1 GM116724NIMHD NIH HHS U54 MD007582
6 · The paper itself

Abstract

We have previously reported that dual 5-HT

Indexed as

Dose-Response Relationship, DrugHumansLigandsMolecular StructurePiperazinesPyridinesReceptor, Serotonin, 5-HT1AReceptors, SerotoninSerotonin 5-HT1 Receptor AgonistsSerotonin AntagonistsStructure-Activity RelationshipLigandsPiperazinesPyridinesReceptor, Serotonin, 5-HT1AReceptors, SerotoninSerotonin 5-HT1 Receptor Agonistsserotonin 7 receptorSerotonin AntagonistsSYA162635-HT subtype ReceptorsDopamine and serotonin receptorsDual 5-HT(1A) and 5-HT(7) receptorsIndanonesPyridinyl piperazineSYA16263

Identifiers

PMID33582388
PMCPMC7984856
OpenAlexW3128727772

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.