Evidence map›Paper›PMID 33582140›Full record

ArticleBiophysical journal2021

Fluorescence depolarization dynamics of ionic strength sensors using time-resolved anisotropy.

Cody P Aplin, Robert C Miller, Taryn M Kay, Ahmed A Heikal, Arnold J Boersma, Erin D Sheets

Abstract read
In one paragraph

Article in Biophysical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cody P AplinDepartment of Chemistry and Biochemistry, University of Minnesota Duluth, Duluth, Minnesota.
Robert C MillerDepartment of Chemistry and Biochemistry, University of Minnesota Duluth, Duluth, Minnesota.
Taryn M KayDepartment of Physics and Astronomy, University of Minnesota Duluth, Duluth, Minnesota.
Ahmed A HeikalDepartment of Chemistry and Biochemistry, University of Minnesota Duluth, Duluth, Minnesota. Electronic address: aaheikal@d.umn.edu.
Arnold J BoersmaDWI-Leibniz Institute for Interactive Materials, Aachen, Germany. Electronic address: boersma@dwi.rwth-aachen.de.
Erin D SheetsDepartment of Chemistry and Biochemistry, University of Minnesota Duluth, Duluth, Minnesota. Electronic address: edsheets@d.umn.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eukaryotic cells exploit dynamic and compartmentalized ionic strength to impact a myriad of biological functions such as enzyme activities, protein-protein interactions, and catalytic functions. Herein, we investigated the fluorescence depolarization dynamics of recently developed ionic strength biosensors (mCerulean3-linker-mCitrine) in Hofmeister salt (KCl, NaCl, NaI, and Na

Indexed as

Biosensing TechniquesFluorescence Resonance Energy TransferAnisotropyFluorescence PolarizationOsmolar Concentration

Identifiers

PMID33582140
PMCPMC8105717

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.