ReviewPharmacology, biochemistry, and behavior2021
Sleep and alertness disturbance and substance use disorders: A bi-directional relation.
Review in Pharmacology, biochemistry, and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 66 citations in OpenAlex.
- Sleep quality and its associated factors among women of reproductive age in Ethiopia: a systematic review and meta-analysis.Frontiers in psychiatry · 2026Pooled it
- Objective and subjective measurement of sleep in people who use substances: Emerging evidence and recommendations from a systematic review.Journal of sleep research · 2025Pooled it
- The association between sleep disturbance and stimulant use: A cross-lagged examination.Addiction (Abingdon, England) · 2026Article
- Blunted light exposure amplitudes in patients with opioid use disorder.Npj biological timing and sleep · 2026Article
- Sleep disturbance is associated with greater subjective and neural negative emotionality in people with alcohol use disorder.Drug and alcohol dependence · 2026Article
- Sleep alterations in substance use disorders: a systematic review and meta-analysis.EClinicalMedicine · 2026Article
- Development of a Cohesive Predictive Model for Substance Use Disorder Rehabilitation Using Passive Digital Biomarkers, Psychological Assessments, and Automated Facial Emotion Recognition: Protocol for a Prospective Cohort Study.JMIR research protocols · 2025Article
- Validity and Reliability of the Korean Version of Substance Use Sleep Scale for Patients With Alcohol Use Disorder.Psychiatry investigation · 2025Article
- Sleep Loss and Substance Use Disorders: An Issue from Adolescents to Adults.Behavioral sciences (Basel, Switzerland) · 2025Review
- Efficacy and safety of laser acupuncture for treating insomnia in major depressive disorder: study protocol for a randomized controlled trial.Frontiers in psychiatry · 2025Article
- Mental health, substance use, and a composite of sleep health in adults, 2018 Ohio behavioral risk factor surveillance system.Sleep medicine · 2024Article
- Substance use and help seeking as coping behaviors among parents and unpaid caregivers of adults in the United States during the COVID-19 pandemic.The American journal of drug and alcohol abuse · 2024Article
- Gender differences in sleep quality among Iranian traditional and industrial drug users.Neurobiology of sleep and circadian rhythms · 2024Article
- Sleep quality and associated factors among people who inject drugs in Iran: a nationwide survey using respondent-driven sampling.BMC public health · 2024Article
- Disentangling heterogeneity in substance use disorder: Insights from genome-wide polygenic scores.Translational psychiatry · 2024Article
- Analysis of novel sleep variable highlights shared genetics of sleep and psychiatric disorders.Sleep · 2024Article
- IUPHAR Review: New strategies for medications to treat substance use disorders.Pharmacological research · 2024Review
- Work hours, weekend working, nonstandard work schedules and sleep quantity and quality: findings from the UK household longitudinal study.BMC public health · 2024Article
- Insomnia symptoms and neurofunctional correlates among adults receiving buprenorphine for opioid use disorder.PloS one · 2024Article
- Substance Use, Sleep Duration, and Health Among Adults in Ohio.Preventing chronic disease · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
The majority of the literature describing the relation of sleep/alertness disturbance and substance use disorders (SUD) has focused on the disruptive effects of substances with abuse liability on sleep and alertness. Rarely have studies or literature reviews assessed or discussed how sleep/alertness disturbance affects substance use. This paper focuses on the sleep/alertness disturbance side of the relation. We argue that the relation is bi-directional and review evidence showing that sleep/alertness disturbance affects all phases of the addiction cycle, including the initiation, maintenance and relapse of SUD. We review a variety of substances across all phases of the addiction cycle and conclude sleep/alertness disturbance is a critical factor in both understanding and treating SUD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.