Evidence map›Paper›PMID 33582059›Full record

ArticleJACC. Cardiovascular imaging2021

Proof-of-Principle Demonstration of Direct Metabolic Imaging Following Myocardial Infarction Using Hyperpolarized 13C CMR.

Andrew Apps, Justin Y C Lau, Jack J J J Miller, Andrew Tyler, Liam A J Young, Andrew J M Lewis, Gareth Barnes, Claire Trumper, Stefan Neubauer, Oliver J Rider and 1 more

Registry-linked trialAbstract readLetter
In one paragraph

Article in JACC. Cardiovascular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06054516 (Hyperpolarized MRSI in Ischemic Heart Disease), which is not on this map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06054516 recruitingnot on this mapstarted 2023, after this paper: background citation

Hyperpolarized MRSI in Ischemic Heart Disease: Metabolic Profiling of the Myocardium

TypeobservationalSponsorHenrik WiggersRan2023 to 2027Enrolled15ConditionsIschemic Heart DiseaseArms13C-enriched pyruvate
3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Molecular contrast agents for post-infarct cardiac remodelling: a contemporary review.European heart journal. Imaging methods and practice · 2026
    Review
  4. Stable electron-irradiated [1-Science advances · 2025
    Article
  5. Review
  6. Hyperpolarized [1-Journal of magnetic resonance open · 2025
    Article
  7. Quo Vadis HyperpolarizedZeitschrift fur medizinische Physik · 2025
    Review
  8. A vendor-neutral EPI sequence for hyperpolarizedMagnetic resonance in medicine · 2024
    Article
  9. Current methods for hyperpolarized [1-Magnetic resonance in medicine · 2024
    Review
  10. Review
  11. Article
  12. The journal of physical chemistry letters · 2024
    Article
  13. Volumetric Patch-Based Super-Resolution Reconstruction of HyperpolarizedIEEE access : practical innovations, open solutions · 2024
    Article
  14. Regional quantification of cardiac metabolism with hyperpolarized [1-Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023
    Article
  15. Regional quantification of cardiac metabolism with hyperpolarized [1-medRxiv : the preprint server for health sciences · 2023
    Article
  16. Article
  17. Review
  18. Review
  19. Imaging Methods: Magnetic Resonance Imaging.Circulation. Cardiovascular imaging · 2023
    Review
  20. Kinetic analysis of multi-resolution hyperpolarizedMagnetic resonance in medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Andrew Apps
Justin Y C Lau
Jack J J J Miller
Andrew Tyler
Liam A J Young
Andrew J M Lewis
Gareth Barnes
Claire Trumper
Stefan Neubauer
Oliver J Rider
Damian J Tyler

Funding

British Heart Foundation FS/10/002/28078British Heart Foundation FS/14/17/30634British Heart Foundation FS/14/54/30946British Heart Foundation FS/17/18/32449British Heart Foundation FS/19/18/34252British Heart Foundation RE/08/004/23915British Heart Foundation RE/13/1/30181British Heart Foundation RG/11/9/28921Medical Research Council G0601490
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Diagnostic ImagingMyocardial InfarctionCarbon IsotopesHumansPredictive Value of TestsCarbon-13Carbon Isotopes

Identifiers

PMID33582059
PMCPMC8184499

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.