Evidence map›Paper›PMID 33581739›Full record

ArticleBMC cancer2021

Feasibility of a multimodal exercise, nutrition, and palliative care intervention in advanced lung cancer.

Manuel Ester, S Nicole Culos-Reed, Amane Abdul-Razzak, Julia T Daun, Delaney Duchek, George Francis, Gwyn Bebb, Jennifer Black, Audra Arlain, Chelsia Gillis and 2 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04575831 (The Feasibility of an Exercise and Nutrition Supportive Care), which is not on this map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04575831 nacompletednot on this map

The Feasibility of an Exercise and Nutrition Supportive Care (Palliative) Intervention for Advanced Non-small-cell Lung Cancer

TypeinterventionalSponsorUniversity of CalgaryRan2019 to 2020Enrolled10ConditionsAdvanced Lung CancerArmsExercise, Nutrition, and Palliative Symptom Management
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Manuel EsterFaculty of Kinesiology, University of Calgary, Calgary, Alberta, Canada.
S Nicole Culos-ReedFaculty of Kinesiology, University of Calgary, Calgary, Alberta, Canada.
Amane Abdul-RazzakDivision of Palliative Medicine, Department of Oncology, University of Calgary, Calgary, Alberta, Canada.
Julia T DaunFaculty of Kinesiology, University of Calgary, Calgary, Alberta, Canada.
Delaney DuchekFaculty of Kinesiology, University of Calgary, Calgary, Alberta, Canada.
George FrancisDivision of Physical Medicine and Rehabilitation, Department of Clinical Neurosciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Gwyn BebbDepartment of Oncology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Jennifer BlackCancer Control Alberta, Alberta Health Services, Calgary, Alberta, Canada.
Audra ArlainCancer Control Alberta, Alberta Health Services, Calgary, Alberta, Canada.
Chelsia GillisCommunity Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Lyle GallowayDepartment of Oncology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Lauren C CapozziFaculty of Kinesiology, University of Calgary, Calgary, Alberta, Canada. lcapozzi@ucalgary.ca.ORCID http://orcid.org/0000-0002-8939-088X
University of Calgary · CAAlberta Health Services · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdvanced lung cancer patients face significant physical and psychological burden leading to reduced physical function and quality of life. Separately, physical activity, nutrition, and palliative symptom management interventions have been shown to improve functioning in this population, however no study has combined all three in a multimodal intervention. Therefore, we assessed the feasibility of a multimodal physical activity, nutrition, and palliative symptom management intervention in advanced lung cancer.

methodsParticipants received an individually tailored 12-week intervention featuring in-person group-based exercise classes, at-home physical activity prescription, behaviour change education, and nutrition and palliative care consultations. Patients reported symptom burden, energy, and fatigue before and after each class. At baseline and post-intervention, symptom burden, quality of life, fatigue, physical activity, dietary intake, and physical function were assessed. Post-intervention interviews examined participant perspectives.

resultsThe multimodal program was feasible, with 44% (10/23) recruitment, 75% (75/100) class attendance, 89% (8/9) nutrition and palliative consult attendance, and 85% (17/20) assessment completion. Of ten participants, 70% (7/10) completed the post-intervention follow-up. Participants perceived the intervention as feasible and valuable. Physical activity, symptom burden, and quality of life were maintained, while tiredness decreased significantly. Exercise classes prompted acute clinically meaningful reductions in fatigue, tiredness, depression, pain, and increases in energy and well-being.

conclusionA multimodal physical activity, nutrition, and palliative symptom management intervention is feasible and shows potential benefits on quality of life that warrant further investigation in a larger cohort trial.

trial registrationNCT04575831 , Registered 05 October 2020 - Retrospectively registered.

Indexed as

Nutritional StatusAgedAged, 80 and overCarcinoma, Non-Small-Cell LungExercise TherapyFeasibility StudiesFemaleHumansLung NeoplasmsMaleMiddle AgedNeoplasm StagingPalliative CareProspective StudiesQuality of LifeAdvanced lung cancerExercise oncologyNutritionQuality of lifeSupportive cancer careSymptom management

Identifiers

PMID33581739
PMCPMC7881342
OpenAlexW3131274556

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.