Evidence map›Paper›PMID 33581461›Full record

ArticleJournal of psychiatric research2021

Using weak supervision and deep learning to classify clinical notes for identification of current suicidal ideation.

Marika Cusick, Prakash Adekkanattu, Thomas R Campion, Evan T Sholle, Annie Myers, Samprit Banerjee, George Alexopoulos, Yanshan Wang, Jyotishman Pathak

Open access · greenAbstract read
In one paragraph

Article in Journal of psychiatric research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
12.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 77 citations in OpenAlex.

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  19. Suicide Phenotyping from Clinical Notes in Safety-Net Psychiatric Hospital Using Multi-Label Classification with Pre-Trained Language Models.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Marika CusickDepartment of Information and Technology Services, Weill Cornell Medicine, New York, USA; Department Population Health Sciences, Weill Cornell Medicine, New York, USA. Electronic address: mac2364@med.cornell.edu.
Prakash AdekkanattuDepartment of Information and Technology Services, Weill Cornell Medicine, New York, USA. Electronic address: pra2008@med.cornell.edu.
Thomas R CampionDepartment of Information and Technology Services, Weill Cornell Medicine, New York, USA; Department Population Health Sciences, Weill Cornell Medicine, New York, USA. Electronic address: thc2015@med.cornell.edu.
Evan T SholleDepartment of Information and Technology Services, Weill Cornell Medicine, New York, USA. Electronic address: evs2008@med.cornell.edu.
Annie MyersDepartment Population Health Sciences, Weill Cornell Medicine, New York, USA. Electronic address: acm4001@med.cornell.edu.
Samprit BanerjeeDepartment Population Health Sciences, Weill Cornell Medicine, New York, USA. Electronic address: sab2028@med.cornell.edu.
George AlexopoulosDepartment of Psychiatry, Weill Cornell Medicine, New York, USA. Electronic address: gsalexop@med.cornell.edu.
Yanshan WangDivision of Digital Health Sciences, Mayo Clinic, MN, USA; Department of Health Sciences Research, Mayo Clinic, MN, USA. Electronic address: Wang.Yanshan@mayo.edu.
Jyotishman PathakDepartment Population Health Sciences, Weill Cornell Medicine, New York, USA; Department of Psychiatry, Weill Cornell Medicine, New York, USA. Electronic address: jyp2001@med.cornell.edu.
Cornell University · USMayo Clinic Health System · US

Funding

National Infrastructure for Standardized and Portable EHR Phenotyping AlgorithmsR01GM105688 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI LUO, YUAN, PATHAK, JYOTISHMAN · 2013 to 2020
$5.7M
Linking VA and non-VA data to study the risk of suicide in chronic pain patients.R01MH121907 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI OSLIN, DAVID W., PATHAK, JYOTISHMAN · 2020 to 2024
$3.6M
Using claims data to study the association between Alzheimer's disease and suicidal behaviorsR01MH119177 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI PATHAK, JYOTISHMAN · 2019 to 2022
$3.3M
Modeling Social Behavior for Healthcare Utilization in DepressionR01MH105384 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI PATHAK, JYOTISHMAN, SHETH, AMIT P · 2015 to 2018
$2.1M
4/4: Leveraging EHR-linked biobanks for deep phenotyping, polygenic risk score modeling, and outcomes analysis in psychiatric disordersR01MH121922 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI PATHAK, JYOTISHMAN · 2019 to 2023
$2.0M
NIGMS NIH HHS R01 GM105688NIMH NIH HHS R01 MH105384NIMH NIH HHS R01 MH119177NIMH NIH HHS R01 MH121907NIMH NIH HHS R01 MH121922
6 · The paper itself

Abstract

Mental health concerns, such as suicidal thoughts, are frequently documented by providers in clinical notes, as opposed to structured coded data. In this study, we evaluated weakly supervised methods for detecting "current" suicidal ideation from unstructured clinical notes in electronic health record (EHR) systems. Weakly supervised machine learning methods leverage imperfect labels for training, alleviating the burden of creating a large manually annotated dataset. After identifying a cohort of 600 patients at risk for suicidal ideation, we used a rule-based natural language processing approach (NLP) approach to label the training and validation notes (n = 17,978). Using this large corpus of clinical notes, we trained several statistical machine learning models-logistic classifier, support vector machines (SVM), Naive Bayes classifier-and one deep learning model, namely a text classification convolutional neural network (CNN), to be evaluated on a manually-reviewed test set (n = 837). The CNN model outperformed all other methods, achieving an overall accuracy of 94% and a F1-score of 0.82 on documents with "current" suicidal ideation. This algorithm correctly identified an additional 42 encounters and 9 patients indicative of suicidal ideation but missing a structured diagnosis code. When applied to a random subset of 5,000 clinical notes, the algorithm classified 0.46% (n = 23) for "current" suicidal ideation, of which 87% were truly indicative via manual review. Implementation of this approach for large-scale document screening may play an important role in point-of-care clinical information systems for targeted suicide prevention interventions and improve research on the pathways from ideation to attempt.

Indexed as

Deep LearningSuicidal IdeationBayes TheoremHumansMachine LearningNatural Language ProcessingDeep learningMachine learningNatural language processingSuicidal ideationWeak supervision

Identifiers

PMID33581461
PMCPMC8009838
OpenAlexW3126592082

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.