Evidence map›Paper›PMID 33581114›Full record

ReviewThe Journal of biological chemistry

Flagging fusion: Phosphatidylserine signaling in cell-cell fusion.

Jarred M Whitlock, Leonid V Chernomordik

Abstract readReview
In one paragraph

Review in The Journal of biological chemistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Age-Associated Metabolomic Changes in Human Spermatozoa.International journal of molecular sciences · 2026
    Article
  5. Article
  6. Article
  7. How Do Cancer Cells Fuse and Why?Advances in experimental medicine and biology · 2026
    Review
  8. Review
  9. Biophysical Considerations in Cell Fusion.Advances in experimental medicine and biology · 2026
    Review
  10. A Brief Introduction into the Biological Phenomenon of Cell-Cell Fusion.Advances in experimental medicine and biology · 2026
    Review
  11. Cell fusion in osteoclastogenesis.Biochemical Society transactions · 2025
    Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Extracellular Vesicle Lipids and Their Role in Delivery.Journal of extracellular biology · 2025
    Review
  18. Article
  19. Review
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jarred M WhitlockSection on Membrane Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA.
Leonid V ChernomordikSection on Membrane Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA. Electronic address: chernoml@mail.nih.gov.

Funding

Protein-mediated membrane remodelingZIAHD001501 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI CHERNOMORDIK, LEONID V. · 2009 to 2025
$30.7M
6 · The paper itself

Abstract

Formations of myofibers, osteoclasts, syncytiotrophoblasts, and fertilized zygotes share a common step, cell-cell fusion. Recent years have brought about considerable progress in identifying some of the proteins involved in these and other cell-fusion processes. However, even for the best-characterized cell fusions, we still do not know the mechanisms that regulate the timing of cell-fusion events. Are they fully controlled by the expression of fusogenic proteins or do they also depend on some triggering signal that activates these proteins? The latter scenario would be analogous to the mechanisms that control the timing of exocytosis initiated by Ca

Indexed as

Cell FusionSignal TransductionExocytosisHumansPhosphatidylserinesVirus InternalizationPhosphatidylserinesmembrane fusionmyogenesisosteoclastphosphatidylserineplacenta

Identifiers

PMID33581114
PMCPMC8005811

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.