Evidence map›Paper›PMID 33580157›Full record

ArticleScientific reports2021

A new heterotropic vascularized model of total urinary bladder transplantation in a rat model.

Arkadiusz Jundziłł, Henryk Witmanowski, Ewa Żary-Sikorska, Jan Adamowicz, Magdalena Bodnar, Andrzej Marszałek, Tomasz Kloskowski, Kaja Męcińska-Jundziłł, Maciej Gagat, Natalia Siedlecka and 2 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Arkadiusz JundziłłChair of Urology and Andrology, Department of Regenerative Medicine, Cell and Tissue Bank, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Skłodowskiej-Curie 9, 85-094, Bydgoszcz, Poland. arekjun@o2.pl.
Henryk WitmanowskiDepartment of Plastic, Reconstructive and Aesthetic Surgery, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Bydgoszcz, Poland.
Ewa Żary-SikorskaDepartment of Microbiology and Food Technology, Faculty of Agriculture and Biotechnology, University of Science and Technology, Bydgoszcz, Poland.
Jan AdamowiczChair of Urology and Andrology, Department of Regenerative Medicine, Cell and Tissue Bank, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Skłodowskiej-Curie 9, 85-094, Bydgoszcz, Poland.
Magdalena BodnarDepartment of Clinical Pathomorphology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Bydgoszcz, Poland.
Andrzej MarszałekDepartment of Clinical Pathology, Poznan University of Medical Sciences and Greater Poland Cancer Center, Poznan, Poland.
Tomasz KloskowskiChair of Urology and Andrology, Department of Regenerative Medicine, Cell and Tissue Bank, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Skłodowskiej-Curie 9, 85-094, Bydgoszcz, Poland.
Kaja Męcińska-JundziłłChair of Dermatology, Sexually Transmitted Diseases and Immunodermatology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Bydgoszcz, Poland.
Maciej GagatDepartment of Embryology and Histology Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Bydgoszcz, Poland.
Natalia SiedleckaChair of Urology and Andrology, Department of Regenerative Medicine, Cell and Tissue Bank, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Skłodowskiej-Curie 9, 85-094, Bydgoszcz, Poland.
Tomasz DrewaChair of Urology and Andrology, Department of Regenerative Medicine, Cell and Tissue Bank, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Skłodowskiej-Curie 9, 85-094, Bydgoszcz, Poland.
Marta PokrywczyńskaChair of Urology and Andrology, Department of Regenerative Medicine, Cell and Tissue Bank, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Skłodowskiej-Curie 9, 85-094, Bydgoszcz, Poland.
Collegium Medicum in Bydgoszcz · PLNicolaus Copernicus University · PLBydgoszcz University of Science and Technology · PLGreater Poland Cancer Center · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study developed a new procedure of urinary bladder transplantation on a rat model (n = 40). Heterotopic urinary bladder transplantation (n = 10) in the right groin vessels was performed. Direct urinary bladder examination, microangiography, histological analysis, and India ink injection were performed to evaluate the proposed method's functionality. Observation time was four weeks. One week after the procedure, the graft survival rate was 80%, two urinary bladders were lost due to anastomosis failure. The rest of the grafts survived two weeks without any complications. Lack of transitional epithelium or smooth muscle layer loss and lack of inflammatory process development were observed. This study was performed in order to obtain the necessary knowledge about urinary bladder transplantation. The proposed technique offers a new approach to the existing orthotropic models.

Indexed as

AnimalsEpithelial CellsFemaleMaleModels, AnimalMuscle, SmoothRatsRats, WistarRegenerationUrinary BladderUrothelium

Identifiers

PMID33580157
PMCPMC7881011
OpenAlexW3126717367

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.