ArticleScientific reports2021
Neural correlates of mating system diversity: oxytocin and vasopressin receptor distributions in monogamous and non-monogamous Eulemur.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 24 citations in OpenAlex.
- The gut microbiome shapes social behaviour across animal species.Nature reviews. Microbiology · 2026Review
- Sex-specific disruption of estrogen receptor alpha (ERα) density in the social brain neural network by Firemaster 550.Journal of the Endocrine Society · 2026Article
- Dissecting the heterogeneity of autism spectrum disorder with sensory behavior, brain, and epigenetic factors.Translational psychiatry · 2025Article
- Neuropeptide receptor distributions in male and femaleBiology letters · 2025Article
- Gestational exposure to FireMaster® 550 (FM 550) disrupts the placenta-brain axis in a socially monogamous rodent species, the prairie vole (Microtus ochrogaster).Molecular and cellular endocrinology · 2023Article
- Review
- Modulation of social behavior by distinct vasopressin sources.Frontiers in endocrinology · 2023Review
- Neural mechanisms involved in female mate choice in invertebrates.Frontiers in endocrinology · 2023Review
- Oxytocin receptors are widely distributed in the prairie vole (Microtus ochrogaster) brain: Relation to social behavior, genetic polymorphisms, and the dopamine system.The Journal of comparative neurology · 2022Article
- Effect of sex and autism spectrum disorder on oxytocin receptor binding and mRNA expression in the dopaminergic pars compacta of the human substantia nigra.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
- Distribution of brain oxytocin and vasopressin V1a receptors in chimpanzees (Pan troglodytes): comparison with humans and other primate species.Brain structure & function · 2022Article
- Fear, love, and the origins of canid domestication: An oxytocin hypothesis.Comprehensive psychoneuroendocrinology · 2022Review
- Neonatal oxytocin gives the tempo of social and feeding behaviors.Frontiers in molecular neuroscience · 2022Review
- Neuroimaging of human and non-human animal emotion and affect in the context of social relationships.Frontiers in behavioral neuroscience · 2022Review
- The neural circuits of monogamous behavior.Frontiers in neural circuits · 2022Review
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Authors and funding
7 authors at 4 institutions in 1 country.
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Abstract
Contemporary theory that emphasizes the roles of oxytocin and vasopressin in mammalian sociality has been shaped by seminal vole research that revealed interspecific variation in neuroendocrine circuitry by mating system. However, substantial challenges exist in interpreting and translating these rodent findings to other mammalian groups, including humans, making research on nonhuman primates crucial. Both monogamous and non-monogamous species exist within Eulemur, a genus of strepsirrhine primate, offering a rare opportunity to broaden a comparative perspective on oxytocin and vasopressin neurocircuitry with increased evolutionary relevance to humans. We performed oxytocin and arginine vasopressin 1a receptor autoradiography on 12 Eulemur brains from seven closely related species to (1) characterize receptor distributions across the genus, and (2) examine differences between monogamous and non-monogamous species in regions part of putative "pair-bonding circuits". We find some binding patterns across Eulemur reminiscent of olfactory-guided rodents, but others congruent with more visually oriented anthropoids, consistent with lemurs occupying an 'intermediary' evolutionary niche between haplorhine primates and other mammalian groups. We find little evidence of a "pair-bonding circuit" in Eulemur akin to those proposed in previous rodent or primate research. Mapping neuropeptide receptors in these nontraditional species questions existing assumptions and informs proposed evolutionary explanations about the biological bases of monogamy.
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