Evidence map›Paper›PMID 33580126›Full record

ArticleScientific reports2021

TRPM8 channel inhibitor-encapsulated hydrogel as a tunable surface for bone tissue engineering.

Tusar Kanta Acharya, Satish Kumar, Nikhil Tiwari, Arijit Ghosh, Ankit Tiwari, Subhashis Pal, Rakesh Kumar Majhi, Ashutosh Kumar, Rashmita Das, Abhishek Singh and 4 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Role of TRP Channels in Cancer-Induced Bone Pain.International journal of molecular sciences · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Tusar Kanta Acharya *School of Biological Sciences, National Institute of Science Education and Research (NISER)-Bhubaneswar, Jatni, Khurda, 752050, Odisha, India.
Satish Kumar *School of Biotechnology, Kalinga Institute of Industrial Technology, Patia, Bhubaneswar, 751024, India.
Nikhil Tiwari *School of Biological Sciences, National Institute of Science Education and Research (NISER)-Bhubaneswar, Jatni, Khurda, 752050, Odisha, India.
Arijit Ghosh *School of Biological Sciences, National Institute of Science Education and Research (NISER)-Bhubaneswar, Jatni, Khurda, 752050, Odisha, India.
Ankit TiwariSchool of Biological Sciences, National Institute of Science Education and Research (NISER)-Bhubaneswar, Jatni, Khurda, 752050, Odisha, India.
Subhashis PalDivision of Endocrinology and Center for Research in Anabolic Skeletal Target in Health and Illness (ASTHI), Central Drug Research Institute (CDRI), Council of Scientific and Industrial Research (CSIR), Lucknow, 226031, India.
Rakesh Kumar MajhiSchool of Biological Sciences, National Institute of Science Education and Research (NISER)-Bhubaneswar, Jatni, Khurda, 752050, Odisha, India.
Ashutosh KumarSchool of Biological Sciences, National Institute of Science Education and Research (NISER)-Bhubaneswar, Jatni, Khurda, 752050, Odisha, India.
Rashmita DasSchool of Biological Sciences, National Institute of Science Education and Research (NISER)-Bhubaneswar, Jatni, Khurda, 752050, Odisha, India.
Abhishek SinghSchool of Biotechnology, Kalinga Institute of Industrial Technology, Patia, Bhubaneswar, 751024, India.
Pradip K MajiDepartment of Polymer and Process Engineering, Indian Institute of Technology Roorkee, Saharanpur Campus, Paper Mill Road, Saharanpur, 247001, Uttar Pradesh, India.
Naibedya ChattopadhyayDivision of Endocrinology and Center for Research in Anabolic Skeletal Target in Health and Illness (ASTHI), Central Drug Research Institute (CDRI), Council of Scientific and Industrial Research (CSIR), Lucknow, 226031, India.
Luna GoswamiSchool of Biotechnology, Kalinga Institute of Industrial Technology, Patia, Bhubaneswar, 751024, India.
Chandan GoswamiSchool of Biological Sciences, National Institute of Science Education and Research (NISER)-Bhubaneswar, Jatni, Khurda, 752050, Odisha, India. chandan@niser.ac.in.
National Institute of Science Education and Research · INHomi Bhabha National Institute · INKIIT University · INCouncil of Scientific and Industrial Research · INIndian Institute of Technology Roorkee · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A major limitation in the bio-medical sector is the availability of materials suitable for bone tissue engineering using stem cells and methodology converting the stochastic biological events towards definitive as well as efficient bio-mineralization. We show that osteoblasts and Bone Marrow-derived Mesenchymal Stem Cell Pools (BM-MSCP) express TRPM8, a Ca

Indexed as

AnimalsBenzamidesBone and BonesBone Marrow CellsCell DifferentiationCells, CulturedFemaleHydrogelsMaleMesenchymal Stem CellsMiceMice, Inbred BALB COsteoblastsOsteogenesisPrimary Cell CultureRatsBenzamidesHydrogelsN-(3-aminopropyl)-2-(((3-methylphenyl) methyl)oxy)-N-(2-thienylmethyl)benzamide hydrochloride saltThiophenesTRPM Cation Channels

Identifiers

PMID33580126
PMCPMC7881029
OpenAlexW3128499690

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.