Evidence map›Paper›PMID 33580111›Full record

ArticleScientific reports2021

SARS-CoV-2 genomic surveillance in Rondônia, Brazilian Western Amazon.

Luan Felipo Botelho-Souza, Felipe Souza Nogueira-Lima, Tárcio Peixoto Roca, Felipe Gomes Naveca, Alcione de Oliveria Dos Santos, Adriana Cristina Salvador Maia, Cicileia Correia da Silva, Aline Linhares Ferreira de Melo Mendonça, Celina Aparecida Bertoni Lugtenburg, Camila Flávia Gomes Azzi and 8 more

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Molecular dynamics of the COVID-19 pandemic in Espirito Santo (Brazil) and border States.Revista do Instituto de Medicina Tropical de Sao Paulo · 2022
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Luan Felipo Botelho-Souza *Oswaldo Cruz Foundation of Rondônia-FIOCRUZ/RO, Porto Velho, RO, 76812 245, Brazil. luan_botelho@hotmail.com.
Felipe Souza Nogueira-Lima *Oswaldo Cruz Foundation of Rondônia-FIOCRUZ/RO, Porto Velho, RO, 76812 245, Brazil.
Tárcio Peixoto Roca *Oswaldo Cruz Foundation of Rondônia-FIOCRUZ/RO, Porto Velho, RO, 76812 245, Brazil.
Felipe Gomes NavecaLeônidas and Maria Deane Institute (ILMD)-FIOCRUZ Amazonas, Manaus, AM, 69027 070, Brazil.
Alcione de Oliveria Dos SantosOswaldo Cruz Foundation of Rondônia-FIOCRUZ/RO, Porto Velho, RO, 76812 245, Brazil.
Adriana Cristina Salvador MaiaRondônia State Government, State Health Secretariat (SESAU/RO), Porto Velho, RO, 76803-620, Brazil.
Cicileia Correia da SilvaRondônia State Government, State Health Secretariat (SESAU/RO), Porto Velho, RO, 76803-620, Brazil.
Aline Linhares Ferreira de Melo MendonçaRondônia State Government, State Health Secretariat (SESAU/RO), Porto Velho, RO, 76803-620, Brazil.
Celina Aparecida Bertoni LugtenburgRondônia Central Public Health Laboratory (LACEN/RO), Porto Velho, RO, 76803-620, Brazil.
Camila Flávia Gomes AzziRondônia State Government, State Health Secretariat (SESAU/RO), Porto Velho, RO, 76803-620, Brazil.
Juliana Loca Furtado FontesRondônia Central Public Health Laboratory (LACEN/RO), Porto Velho, RO, 76803-620, Brazil.
Suelen CavalcanteRondônia Central Public Health Laboratory (LACEN/RO), Porto Velho, RO, 76803-620, Brazil.
Rita de Cássia Pontello RampazzoInstitute of Molecular Biology of Paraná-IBMP, Curitiba, PR, 81350-010, Brazil.
Caio Henrique Nemeth SantosRondônia State Government, State Health Secretariat (SESAU/RO), Porto Velho, RO, 76803-620, Brazil.
Alice Paula Di Sabatino GuimarãesOswaldo Cruz Foundation of Rondônia-FIOCRUZ/RO, Porto Velho, RO, 76812 245, Brazil.
Fernando Rodrigues MáximoRondônia State Government, State Health Secretariat (SESAU/RO), Porto Velho, RO, 76803-620, Brazil.
Juan Miguel Villalobos-SalcedoOswaldo Cruz Foundation of Rondônia-FIOCRUZ/RO, Porto Velho, RO, 76812 245, Brazil.
Deusilene Souza VieiraOswaldo Cruz Foundation of Rondônia-FIOCRUZ/RO, Porto Velho, RO, 76812 245, Brazil.

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico grant 403276/2020-9Conselho Nacional de Desenvolvimento Científico e Tecnológico grant 440856/2016-7Coordenação de Aperfeiçoamento de Pessoal de Nível Superior grant 88881.130825/2016-01Coordenação de Aperfeiçoamento de Pessoal de Nível Superior grant 88887.130823/2016-00FGN is funded by Fundação de Amparo à Pesquisa do Estado do Amazonas - FAPEAM PCTI-EmergeSaúde/AM call N°005/2020FGN is funded by Fundação de Amparo à Pesquisa do Estado do Amazonas - FAPEAM Rede Genômica de Vigilância em Saúde - REGESAMInova Fiocruz/Fundação Oswaldo Cruz Grant VPPCB-007-FIO-18-2-30 - Geração de conhecimento
6 · The paper itself

Abstract

SARS-CoV-2 has spread rapidly around the world, with Brazil currently considered an epicenter of the pandemic. The Northern region has the second highest incidence coefficient, as well as the third highest mortality rate in the country. This study aimed to investigate information about the evolutionary history of epidemic spread and genetic aspects of strains isolated on the Western Amazon, in the State of Rondônia, Brazil. It was possible to detect a total of 22 mutations. Some of these alterations may possibly be related to effects on transmissibility, the fidelity of RNA replication, the ability of cancer patients to respond to infection, beyond a mutation that emerged after the introduction of SARS-CoV-2 in Rondônia. At least two events of introduction were detected, corresponding to the B.1 and B.1.1 European lineages. An introduction was observed possibly through Argentina, where strains originated that circulated in the Minas Gerais and Ceará Brazilian states, prior to Rondônia (B.1.), as well as through the Minas Gerais state and the Federal District, which gave rise to strains that spread to Rondônia, from the capital to more rural parts of the state (B.1.1.). The findings show the need to monitor the genetic epidemiology of COVID-19, in order to surveil the virus's evolution, dispersion and diversity.

Indexed as

Mutation RatePhylogenyBrazilCOVID-19HumansSARS-CoV-2Viral ProteinsViral Proteins

Identifiers

PMID33580111
PMCPMC7881028

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.