ArticleScientific reports2021
Comparative transcriptome analysis of Rheum australe, an endangered medicinal herb, growing in its natural habitat and those grown in controlled growth chambers.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed, 28 citations in OpenAlex.
- Dissecting alternative splicing patterns of the Rheum palmatum complex with different contents of medicinal constituents.BMC genomics · 2025Article
- Involvement of Ethylene in Adventitious Root Formation of Red-Stalked Rhubarb In Vitro.International journal of molecular sciences · 2025Article
- Exploring Genetic Diversity and Inter-/Intraspecific Polymorphism inInternational journal of molecular sciences · 2025Article
- Article
- Comparative transcriptome analysis and HPLC reveal candidate genes associated with synthesis of bioactive constituents inPhysiology and molecular biology of plants : an international journal of functional plant biology · 2024Article
- Insights into the regulation of energy metabolism during the seed-to-seedling transition in marine angiospermFrontiers in plant science · 2023Article
- Growth Cessation and Dormancy Induction in Micropropagated Plantlets ofInternational journal of molecular sciences · 2022Article
- Regulation of the Bud Dormancy Development and Release in Micropropagated Rhubarb 'Malinowy'.International journal of molecular sciences · 2022Article
- Transcriptomic analyses provide new insights into green and purple color pigmentation inPeerJ · 2022Article
- Comparative transcriptome analysis of different tissues of Rheum tanguticum Maxim. ex Balf. (Polygonaceae) reveals putative genes involved in anthraquinone biosynthesis.Genetics and molecular biology · 2022Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rheum australe is an endangered medicinal herb of high altitude alpine region of Himalayas and is known to possess anti-cancerous properties. Unlike many herbs of the region, R. australe has broad leaves. The species thrives well under the environmental extremes in its niche habitat, therefore an understanding of transcriptome of R. australe to environmental cues was of significance. Since, temperature is one of the major environmental variables in the niche of R. australe, transcriptome was studied in the species growing in natural habitat and those grown in growth chambers maintained at 4 °C and 25 °C to understand genes associated with different temperatures. A total of 39,136 primarily assembled transcripts were obtained from 10,17,74,336 clean read, and 21,303 unigenes could match to public databases. An analysis of transcriptome by fragments per kilobase of transcript per million, followed by validation through qRT-PCR showed 22.4% up- and 22.5% down-regulated common differentially expressed genes in the species growing under natural habitat and at 4 °C as compared to those at 25 °C. These genes largely belonged to signaling pathway, transporters, secondary metabolites, phytohormones, and those associated with cellular protection, suggesting their importance in imparting adaptive advantage to R. australe in its niche.
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