ArticleNature communications2021
Persistence of self-reactive CD8+ T cells in the CNS requires TOX-dependent chromatin remodeling.
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 36 citations in OpenAlex.
- Scalable transcription factor mapping uncovers the regulatory dynamics of natural and synthetic transcription factors in human T cell states.bioRxiv : the preprint server for biology · 2025Article
- Oligodendrocyte-derived IL-33 regulates self-reactive CD8+ T cells in CNS autoimmunity.The Journal of experimental medicine · 2025Article
- Microglia activation orchestrates CXCL10-mediated CD8Nature neuroscience · 2025Article
- Low expression of TOX predicts poor prognosis of patients with breast cancer in the real world: A retrospective study.Heliyon · 2025Article
- Cross-talk between aging resilience pathways and autoimmunity onset.Frontiers in immunology · 2025Review
- TOX, through a glass, darkly.Frontiers in immunology · 2025Review
- Extraislet expression of islet antigen boosts T cell exhaustion to partially prevent autoimmune diabetes.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Single-cell analysis reveals expanded CD8Brain communications · 2024Article
- T cells in health and disease.Signal transduction and targeted therapy · 2023Review
- Persistent virus-specific and clonally expanded antibody-secreting cells respond to induced self-antigen in the CNS.Acta neuropathologica · 2023Article
- Immune checkpoint receptors in autoimmunity.Current opinion in immunology · 2023Review
- Tox induces T cell IL-10 production in a BATF-dependent manner.Frontiers in immunology · 2023Article
- The immunology of multiple sclerosis.Nature reviews. Immunology · 2022Review
- Article
- Gene Regulatory Circuits in Innate and Adaptive Immune Cells.Annual review of immunology · 2022Review
- High miR203a-3p and miR-375 expression in the airways of smokers with and without COPD.Scientific reports · 2022Article
- Regulation of activated T cell survival in rheumatic autoimmune diseases.Nature reviews. Rheumatology · 2022Review
- T cell exhaustion-a memory locked behind scars.Nature immunology · 2021Article
- Not-so-opposite ends of the spectrum: CD8Nature immunology · 2021Review
- Schrödinger's T Cells: Molecular Insights Into Stemness and Exhaustion.Frontiers in immunology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
Abstract
Self-reactive CD8
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.