Evidence map›Paper›PMID 33579908›Full record

ArticleNature communications2021

Hypothermic machine perfusion before viability testing of previously discarded human livers.

Otto B van Leeuwen, Yvonne de Vries, Vincent E de Meijer, Robert J Porte

Abstract readLetterComment
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Machine perfusion in liver transplantation.The Cochrane database of systematic reviews · 2023
    Pooled it
  2. A diagnostic accuracy study of mitochondrial FMN during hypothermic oxygenated perfusion to guide liver utilization and avoid normothermic assessment.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2026
    Article
  3. Review
  4. Viability Assessment During Normothermic Machine Liver Perfusion: A Literature Review.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Sequential hypothermic and normothermic machine perfusion enables safe transplantation of high-risk donor livers.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022
    Observational
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Otto B van LeeuwenDepartment of Surgery, Section of Hepatobiliary Surgery & Liver Transplantation, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.ORCID 0000-0002-8600-0479
Yvonne de VriesDepartment of Surgery, Section of Hepatobiliary Surgery & Liver Transplantation, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
Vincent E de MeijerDepartment of Surgery, Section of Hepatobiliary Surgery & Liver Transplantation, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.ORCID 0000-0002-7900-5917
Robert J PorteDepartment of Surgery, Section of Hepatobiliary Surgery & Liver Transplantation, University Medical Center Groningen, University of Groningen, Groningen, Netherlands. r.j.porte@umcg.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

LiverLiver TransplantationHumansPerfusion

Identifiers

PMID33579908
PMCPMC7881206

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.