ArticleJournal of vestibular research : equilibrium & orientation2021
Association between vestibular function and rotational spatial orientation perception in older adults.
Article in Journal of vestibular research : equilibrium & orientation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Path Integration in Alzheimer's Disease: Orientation, Movement, and Theta Rhythmicity.Annual review of neuroscience · 2026Review
- Autism associatedbioRxiv : the preprint server for biology · 2026Article
- Spatial Orientation Impairment in Patients With Bilateral Vestibulopathy and Persistent Postural-Perceptual Dizziness.Brain and behavior · 2025Article
- Diagnostic Utility of Vestibular Markers in Identifying Mild Cognitive Impairment and Early Alzheimer's Disease in Older Adults.Journal of clinical medicine · 2025Article
- The Vestibulo-Ocular Reflex is Associated With Visuospatial Dysfunction in Patients With Parkinson's Disease.Brain and behavior · 2025Article
- Spatial anxiety contributes to the dizziness-related handicap of adults with peripheral vestibular disease.Frontiers in neurology · 2024Article
- Effects of Unilateral Audio-Vestibular Insufficiency on Spatial Hearing.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023Article
- Vestibular damage affects the precision and accuracy of navigation in a virtual visual environment.Brain communications · 2023Article
- Vestibular perceptual testing from lab to clinic: a review.Frontiers in neurology · 2023Review
- Spatial orientation, postural control and the vestibular system in healthy elderly and Alzheimer's dementia.PeerJ · 2023Review
- Navigation strategies in patients with vestibular loss tested in a virtual reality T-maze.Journal of neurology · 2022Article
- Anxiety and Motion Sickness Susceptibility May Influence the Ability to Update Orientation in the Horizontal Plane of Healthy Subjects.Frontiers in integrative neuroscience · 2021Article
- Getting LOST: A conceptual framework for supporting and enhancing spatial navigation in aging.Wiley interdisciplinary reviews. Cognitive scienceReview
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundSpatial orientation is a complex process involving vestibular sensory input and possibly cognitive ability. Previous research demonstrated that rotational spatial orientation was worse for individuals with profound bilateral vestibular dysfunction.
objectiveDetermine whether rotational and linear vestibular function were independently associated with large amplitude rotational spatial orientation perception in healthy aging.
methodsTests of rotational spatial orientation accuracy and vestibular function [vestibulo-ocular reflex (VOR), ocular and cervical vestibular evoked myogenic potentials (VEMP)] were administered to 272 healthy community-dwelling adults participating in the Baltimore Longitudinal Study of Aging. Using a mixed model multiple linear regression we regressed spatial orientation errors on lateral semicircular canal function, utricular function (ocular VEMP), and saccular function (cervical VEMP) in a single model controlling for rotation size, age, and sex.
resultsAfter adjusting for age, and sex, individuals with bilaterally low VOR gain (β= 20.9, p = 0.014) and those with bilaterally absent utricular function (β= 9.32, p = 0.017) made significantly larger spatial orientation errors relative to individuals with normal vestibular function.
conclusionsThe current results demonstrate for the first time that either bilateral lateral semicircular canal dysfunction or bilateral utricular dysfunction are associated with worse rotational spatial orientation. We also demonstrated in a healthy aging cohort that increased age also contributes to spatial orientation ability.
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