ArticleJournal of Alzheimer's disease : JAD2021
Age-Related Hearing Loss, Neuropsychological Performance, and Incident Dementia in Older Adults.
Article in Journal of Alzheimer's disease : JAD, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 28 citations in OpenAlex.
- A precision medicine tool to understand who responds best to hearing aids in late-life depression.International journal of geriatric psychiatry · 2022Trial
- Hearing Rehabilitative Treatment for Older Adults With Comorbid Hearing Loss and Depression: Effects on Depressive Symptoms and Executive Function.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2022Trial
- Association of self-reported hearing loss and tinnitus with brain structure and cognitive function: a population-based cross-sectional analysis from the Study of Health in Pomerania (SHIP).Alzheimer's research & therapy · 2026Article
- A Phenome-Wide Comorbidity Atlas of Age-Related Hearing Loss, Speech-in-Noise Deficits, and Tinnitus: Distinguishing Causal Signals from Correlation.Journal of the Association for Research in Otolaryngology : JARO · 2025Article
- Cognitive function trajectories and influencing factors in Chinese older adults with self-reported hearing impairment: findings from CHARLS 2013-2020.BMC geriatrics · 2025Article
- Hearing Loss, Brain Structure, Cognition, and Dementia Risk in the Framingham Heart Study.JAMA network open · 2025Article
- Self-reported hearing loss is associated with faster cognitive and functional decline but not diagnostic conversion in the ADNI cohort.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Subjective hearing loss is not associated with an increased risk of Alzheimer's disease dementia.Heliyon · 2024Article
- The Association between Untreated and Treated Hearing Loss and Cognitive Performance in Men and Women Aged 60-96 Years: Data from the Swedish "Good Aging in Skåne" Population Study.Journal of clinical medicine · 2024Article
- Association between cognitive dysfunction and diabetes in patients over 65 years old: a cross-sectional study using propensity score matching.Journal of rehabilitation medicine · 2024Article
- Knowledge, Attitudes, and Practice of General Practitioners Toward Screening of Age-Related Hearing Loss in Community: A Cross-Sectional Study in Shanghai, China.Journal of multidisciplinary healthcare · 2024Article
- Is Age a Limiting Factor for Audiological Results in Active Middle Ear Implants?Journal of personalized medicine · 2023Article
- Association Between Hearing Loss and Multiple Negative Emotional States in the US Hispanic Population.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2023Article
- Effect of cochlear implantation on cognitive decline and quality of life in younger and older adults with severe-to-profound hearing loss.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022Article
- The Relationship Between Hearing and Mild Behavioral Impairment and the Influence of Sex: A Study of Older Adults Without Dementia from the COMPASS-ND Study.Journal of Alzheimer's disease reports · 2022Article
- Hearing Impairment and Cognition in an Aging World.Journal of the Association for Research in Otolaryngology : JARO · 2021Review
- The Longitudinal Association of Subclinical Hearing Loss With Cognition in the Health, Aging and Body Composition Study.Frontiers in aging neuroscience · 2021Article
- Hearing Loss and Cognition: What We Know and Where We Need to Go.Frontiers in aging neuroscience · 2021Review
- Age-Related Disparities in the Treatment of Borderline/Mild Hearing Loss in the United States.OTO openArticle
- Association Between Age-Related Sensory and Metabolic Hearing Loss and Cognitive Performance.Trends in hearingArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundAge-related hearing loss (HL) has been associated with dementia, though the neurocognitive profile of individuals with HL is poorly understood.
objectiveTo characterize the neurocognitive profile of HL.
methodsN = 8,529 participants from the National Alzheimer's Coordinating Center ≥60 years and free of cognitive impairment who were characterized as Untreated-, Treated-, or No HL. Outcomes included executive function (Trail Making Test [TMT] Part B), episodic memory (Immediate/Delayed Recall), language fluency (Vegetables, Boston Naming Test), and conversion to dementia. Regression models were fit to examine associations between HL and neurocognitive performance at baseline. Cox proportional hazards models examined the links between HL, neurocognitive scores, and development of dementia over follow-up.
resultsAt baseline, those with Untreated HL (versus No HL) had worse neurocognitive performance per standardized difference on executive function (TMT Part B [mean difference = 0.05 (95% CI 0.00, 0.10)]) and language fluency (Vegetables [mean difference = -0.07 (95% CI -0.14, -0.01)], Boston Naming Test [mean difference = -0.07 (95% CI -0.13, -0.01)]). No differences in these neurocognitive performance scores were demonstrated between Treated HL and No HL groups other than MMSE [mean difference = -0.06 (95% CI -0.12, 0.00)]. Through follow-up, executive dysfunction differed by hearing group (χ2(2) = 46.08, p < 0.0001) and was present among 39.12% in No HL, 44.85% in Untreated HL, and 49.40% in Treated HL. Worse performance across all cognitive domains predicted incident dementia.
conclusionThe observed association between Untreated HL and lower cognitive ability that improved when hearing aids were worn may reflect an inability to hear the test instructions. Future studies using cognitive assessments validated for use in HL are needed to evaluate the neuropsychological profile of HL and identify individuals at risk for dementia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.