Evidence map›Paper›PMID 33579804›Full record

Trial reportJournal of nuclear medicine : official publication, Society of Nuclear Medicine2021

A Prospective, Randomized, Double-Blind Study to Evaluate the Safety, Biodistribution, and Dosimetry of

Wenjia Zhu, Yuejuan Cheng, Ru Jia, Hong Zhao, Chunmei Bai, Jianming Xu, Shaobo Yao, Li Huo

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05410743 (A Phase 1/2, Non-Randomized, Open-Label, Dose Escalation, Single-Center Study to Determine the Safety, Bio-distribution, and Preliminary Effectiveness and Efficacy of 177Lu-TATE-EB-01(LNC1010)in Adult Subjects With SSTR2-positive Tumors), which is not on this map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05410743 phase1 / phase2completednot on this mapstarted 2022, after this paper: background citation

A Phase 1/2, Non-Randomized, Open-Label, Dose Escalation, Single-Center Study to Determine the Safety, Bio-distribution, and Preliminary Effectiveness and Efficacy of 177Lu-TATE-EB-01(LNC1010)in Adult Subjects With SSTR2-positive Tumors

TypeinterventionalSponsorThe First Affiliated Hospital of Xiamen UniversityRan2022 to 2025Enrolled30ConditionsSSTR2-positive TumorsArms177Lu-LNC1010 1, 177Lu-LNC1010 2, 177Lu-LNC1010 3, 177Lu-LNC1010 4
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 36 citations in OpenAlex.

  1. A prospective randomized, double-blind study to evaluate the diagnostic efficacy ofEuropean journal of nuclear medicine and molecular imaging · 2022
    Trial
  2. Article
  3. Article
  4. Review
  5. Synthesis, preclinical evaluation, and clinical translation of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  6. Article
  7. Synthesis and preclinical evaluation of [European journal of nuclear medicine and molecular imaging · 2025
    Article
  8. Review
  9. Article
  10. Review
  11. Design, Preclinical Evaluation, and Clinical Translation ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Article
  12. SSTR antagonist [European journal of nuclear medicine and molecular imaging · 2024
    Article
  13. First preclinical evaluation of [EJNMMI radiopharmacy and chemistry · 2023
    Article
  14. Review
  15. Development of thePharmaceutics · 2023
    Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Wenjia ZhuDepartment of Nuclear Medicine, Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Peking Union Medical College Hospital, CAMS and PUMC, Beijing, China.
Yuejuan ChengDepartment of Oncology, Peking Union Medical College Hospital, Beijing, China.
Ru JiaDepartment of Gastrointestinal Oncology, Fifth Medical Center, General Hospital of PLA, Beijing, China.
Hong ZhaoDepartment of Hepatobiliary Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; and.
Chunmei BaiDepartment of Oncology, Peking Union Medical College Hospital, Beijing, China.
Jianming XuDepartment of Gastrointestinal Oncology, Fifth Medical Center, General Hospital of PLA, Beijing, China.
Shaobo YaoDepartment Nuclear Medicine, First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China.
Li HuoDepartment of Nuclear Medicine, Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Peking Union Medical College Hospital, CAMS and PUMC, Beijing, China; huoli@pumch.cn.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNChinese PLA General Hospital · CNFirst Affiliated Hospital of Fujian Medical University · CNPeking Union Medical College Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Neuroendocrine TumorsPeptides, CyclicRadiometrySafetyAcetatesAdultAgedDouble-Blind MethodFemaleGallium RadioisotopesHeterocyclic Compounds, 1-RingHumansMaleMiddle AgedOrganometallic CompoundsPositron Emission Tomography Computed Tomography1-(1,3-carboxypropyl)-4,7-carboxymethyl-1,4,7-triazacyclononaneAcetatesGallium RadioisotopesHeterocyclic Compounds, 1-RingOrganometallic CompoundsPeptides, Cyclic68Ga-DOTA-LM368Ga-NODAGA-LM3neuroendocrine tumorPET/CTsomatostatin receptor antagonist

Identifiers

PMID33579804
PMCPMC8724897
OpenAlexW3127019719

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.