Evidence map›Paper›PMID 33579736›Full record

ArticleJournal for immunotherapy of cancer2021

Intratumoral virotherapy with 4-1BBL armed modified vaccinia Ankara eradicates solid tumors and promotes protective immune memory.

Maria Hinterberger, Raphael Giessel, Giovanna Fiore, Fabienne Graebnitz, Barbara Bathke, Sonia Wennier, Paul Chaplin, Ignacio Melero, Mark Suter, Henning Lauterbach and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal for immunotherapy of cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

  1. Newly identified oncolytic VSV-GP-specific CD8Molecular therapy. Oncology · 2025
    Article
  2. Review
  3. Review
  4. The danger theory of immunity revisited.Nature reviews. Immunology · 2024
    Review
  5. Review
  6. Review
  7. Review
  8. Personalizing Oncolytic Immunovirotherapy Approaches.Molecular diagnosis & therapy · 2024
    Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. CD137 (4-1BB) costimulation of CD8Nature communications · 2021
    Article
  16. Article
  17. Immunogenic Cell Death-Based Cancer Vaccines.Frontiers in immunology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 3 countries.

Maria HinterbergerBavarian Nordic GmbH, Planegg, Germany mahi@bavarian-nordic.com jome@bavarian-nordic.com.ORCID 0000-0003-2672-9134
Raphael GiesselBavarian Nordic GmbH, Planegg, Germany.
Giovanna FioreBavarian Nordic GmbH, Planegg, Germany.
Fabienne GraebnitzBavarian Nordic GmbH, Planegg, Germany.
Barbara BathkeBavarian Nordic GmbH, Planegg, Germany.
Sonia WennierBavarian Nordic GmbH, Planegg, Germany.
Paul ChaplinBavarian Nordic GmbH, Planegg, Germany.
Ignacio MeleroProgram of Immunology and Immunotherapy, Cima Universidad de Navarra, Pamplona, Spain.ORCID 0000-0002-1360-348X
Mark SuterBavarian Nordic GmbH, Planegg, Germany.
Henning LauterbachBavarian Nordic GmbH, Planegg, Germany.
Pedro BerraondoProgram of Immunology and Immunotherapy, Cima Universidad de Navarra, Pamplona, Spain.ORCID 0000-0001-7410-1865
Hubertus HochreinBavarian Nordic GmbH, Planegg, Germany.
José Medina-EcheverzBavarian Nordic GmbH, Planegg, Germany mahi@bavarian-nordic.com jome@bavarian-nordic.com.
Bavarian Nordic (Germany) · DENavarre Institute of Health Research · ESUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

4-1BB LigandAnimalsAntigens, NeoplasmCD8-Positive T-LymphocytesCell Line, TumorCloning, MolecularCombined Modality TherapyDrug SynergismFemaleImmunologic MemoryMelanoma, ExperimentalMiceOncolytic VirotherapyTreatment OutcomeTumor MicroenvironmentVaccinia virus4-1BB LigandAntigens, Neoplasmimmunotherapylocal virotherapylymphocyte activationlymphocytestumor-infiltratingvaccination

Identifiers

PMID33579736
PMCPMC7883866
OpenAlexW3128608697

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.