Evidence map›Paper›PMID 33579724›Full record

Observational studyJournal of immunology (Baltimore, Md. : 1950)2021

IgG Epitopes Processed and Presented by IgG

Li-En Hsieh, John Sidney, Jane C Burns, David L Boyle, Gary S Firestein, Yoav Altman, Alessandro Sette, Alessandra Franco

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in Journal of immunology (Baltimore, Md. : 1950), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. The yin/yang balance of the MHC-selfFrontiers in immunology · 2022
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Li-En HsiehDepartment of Pediatrics, School of Medicine, University of California San Diego, La Jolla, CA 92093.ORCID 0000-0003-1179-2229
John SidneyDivision of Vaccine Discovery, La Jolla Institute for Immunology, La Jolla, CA 92037.ORCID 0000-0002-0987-405X
Jane C BurnsDepartment of Pediatrics, School of Medicine, University of California San Diego, La Jolla, CA 92093.ORCID 0000-0001-5679-1217
David L BoyleDepartment of Medicine, School of Medicine, University of California San Diego, La Jolla, CA 92093; and.ORCID 0000-0002-1454-2834
Gary S FiresteinDepartment of Medicine, School of Medicine, University of California San Diego, La Jolla, CA 92093; and.
Yoav AltmanSanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037.ORCID 0000-0001-6075-1111
Alessandro SetteDivision of Vaccine Discovery, La Jolla Institute for Immunology, La Jolla, CA 92037.
Alessandra FrancoDepartment of Pediatrics, School of Medicine, University of California San Diego, La Jolla, CA 92093; alfranco@health.ucsd.edu.
University of California San Diego · USLa Jolla Institute for Immunology · USSanford Burnham Prebys Medical Discovery Institute · US

Funding

Tumor Microenvironment and Cancer ImmunologyP30CA030199 · NCI · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI ELENA B PASQUALE · 1985 to 2026
$107.2M
UC San Diego Clinical and Translational Research InstituteUL1TR001442 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S, HOGARTH, MICHAEL · 2015 to 2024
$88.3M
How immunodominant Fc peptide epitopes expand natural regulatory T cells and downregulate inflammationR01AI143586 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FRANCO, ALESSANDRA I · 2019 to 2021
$1.3M
NCATS NIH HHS UL1 TR001442NCI NIH HHS P30 CA030199NIAID NIH HHS R01 AI143586
6 · The paper itself

Abstract

We described a human regulatory T cell (Treg) population activated by IgG

Indexed as

AdultAgedAntigen PresentationArthritis, RheumatoidDendritic CellsEpitopes, B-LymphocyteFemaleHistocompatibility Antigens Class IIHumansImmunoglobulin Fc FragmentsImmunoglobulin GLymphocyte ActivationMaleMiddle AgedPrimary Cell CultureT-Lymphocytes, RegulatoryEpitopes, B-LymphocyteHistocompatibility Antigens Class IIImmunoglobulin Fc FragmentsImmunoglobulin G

Identifiers

PMID33579724
PMCPMC7939040
OpenAlexW3128190649

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.