Evidence map›Paper›PMID 33579683›Full record

ArticleApplied and environmental microbiology2021

A postbiotic consisting of heat-treated lactobacilli has a bifidogenic effect in pure culture and in human fermented faecal communities.

Alicja K Warda, Adam G Clooney, Feargal Ryan, Pedro H de Almeida Bettio, Giulio Di Benedetto, Reynolds P Ross, Colin Hill

Open access · hybridAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. A Postbiotic ContainingMicroorganisms · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Application ofFoods (Basel, Switzerland) · 2025
    Article
  7. Antiprotozoal Effects ofPathogens (Basel, Switzerland) · 2025
    Article
  8. A Postbiotic Derived fromFoods (Basel, Switzerland) · 2025
    Article
  9. Review
  10. Article
  11. Microbes as medicine.Annals of the New York Academy of Sciences · 2024
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Nutrients · 2023
    Article
  17. Article
  18. Frontiers in microbiology · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Alicja K WardaAPC Microbiome Ireland, University College Cork, Cork, Ireland.ORCID https://orcid.org/0000-0001-8317-6455
Adam G ClooneyAPC Microbiome Ireland, University College Cork, Cork, Ireland.
Feargal RyanAPC Microbiome Ireland, University College Cork, Cork, Ireland.ORCID https://orcid.org/0000-0002-1565-4598
Pedro H de Almeida BettioAPC Microbiome Ireland, University College Cork, Cork, Ireland.
Giulio Di BenedettoAPC Microbiome Ireland, University College Cork, Cork, Ireland.
Reynolds P RossAPC Microbiome Ireland, University College Cork, Cork, Ireland.
Colin HillAPC Microbiome Ireland, University College Cork, Cork, Ireland. c.hill@ucc.ie.ORCID https://orcid.org/0000-0002-8527-1445
University College Cork · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gut microbiota has a significant impact on host health. Dietary interventions using probiotics, prebiotics and postbiotics have the potential to alter microbiota composition and function. Other therapeutic interventions such as antibiotics and faecal microbiota transplantation have also been shown to significantly alter the microbiota and its metabolites. Supplementation of a faecal fermentation model of the human gut with a postbiotic product Lactobacillus LB led to changes in microbiome composition (i.e. increase in beneficial bifidobacteria) and associated metabolic changes (i.e. increased acid production). Lactobacillus LB is a heat-treated preparation of cellular biomass and a fermentate generated by

Identifiers

PMID33579683
PMCPMC8091120
OpenAlexW3127939620

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.