ArticleAntimicrobial resistance and infection control2021
NeoCLEAN: a multimodal strategy to enhance environmental cleaning in a resource-limited neonatal unit.
Article in Antimicrobial resistance and infection control, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Gram-negative neonatal sepsis in low- and lower-middle-income countries and WHO empirical antibiotic recommendations: A systematic review and meta-analysis.PLoS medicine · 2021Pooled it
- The impact of enhanced cleaning on bacterial contamination of the hospital environmental surfaces: a clinical trial in critical care unit in an Egyptian hospital.Antimicrobial resistance and infection control · 2024Trial
- Impact of targeted infection prevention and control interventions on bloodstream infections and colonization with carbapenem-resistant organisms among hospitalized neonates, Bangladesh, 2023-2024.Antimicrobial resistance and infection control · 2026Article
- Developing and implementing a family-led infection prevention bundle for hospitalized neonates.Antimicrobial resistance and infection control · 2026Article
- Parental involvement in infection prevention and control in low- and middle-income country neonatal units: a scoping review.Antimicrobial resistance and infection control · 2025Article
- Risk Factors for Health Care-Associated Bloodstream Infections in NICUs.JAMA network open · 2025Article
- Comparative analysis of routine clinical debriefings and incident reports: insights for patient safety and teamwork enhancement.International journal for quality in health care : journal of the International Society for Quality in Health Care · 2025Article
- Comparative effectiveness of a multimodal intervention package on surface cleaning and disinfection in Brazilian neonatal intensive care units.Frontiers in public health · 2025Article
- Prevalence, Characterization, and Epidemiological Relationships between ESBL and Carbapenemase-ProducingAntibiotics (Basel, Switzerland) · 2024Article
- Research priorities to strengthen environmental cleaning in healthcare facilities: the CLEAN Group Consensus.Antimicrobial resistance and infection control · 2024Article
- Infection prevention and control and related practices in African neonatal units: The Pan-African neonatal care assessment study (PANCAS).International journal of hygiene and environmental health · 2024Article
- ATP-based assessments of recent cleaning and disinfection for high-touch surfaces in low-resource shared toilets.NPJ clean water · 2024Article
- Improving infection control in a veterinary hospital: a detailed study on patterns of faecal contamination to inform changes in practice.Irish veterinary journal · 2023Article
- Development and evaluation of prevention bundle for neonatal healthcare-associated infections: an interventional study.F1000Research · 2023Article
- Impact of a multi-strain probiotic administration on peri-rectal colonization with drug-resistant Gram-negative bacteria in preterm neonates.Frontiers in pediatrics · 2022Article
- Healthcare-Associated Infection Prevention Interventions for Neonates in Resource-Limited Settings.Frontiers in pediatrics · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
Abstract
backgroundContamination of the hospital environment contributes to neonatal bacterial colonization and infection. Cleaning of hospital surfaces and equipment is seldom audited in resource-limited settings.
methodsA quasi-experimental study was conducted to assess the impact of a multimodal cleaning intervention for surfaces and equipment in a 30-bed neonatal ward. The intervention included cleaning audits with feedback, cleaning checklists, in-room cleaning wipes and training of staff and mothers in cleaning methods. Cleaning adequacy was evaluated for 100 items (58 surfaces, 42 equipment) using quantitative bacterial surface cultures, adenosine triphosphate bioluminescence assays and fluorescent ultraviolet markers, performed at baseline (P1, October 2019), early intervention (P2, November 2019) and late intervention (P3, February 2020).
resultsEnvironmental swabs (55/300; 18.3%) yielded growth of 78 potential neonatal pathogens with Enterococci, S. marcescens, K. pneumoniae, S. aureus and A. baumannii predominating. Highest aerobic colony counts were noted from moist surfaces such as sinks, milk kitchen surfaces, humidifiers and suction tubing. The proportion of surfaces and equipment exhibiting no bacterial growth increased between phases (P1 = 49%, P2 = 66%, P3 = 69%; p = 0.007). The proportion of surfaces and equipment meeting the ATP "cleanliness" threshold (< 200 relative light units) increased over time (P1 = 40%, P2 = 54%, P3 = 65%; p = 0.002), as did the UV marker removal rate (P1 = 23%, P2 = 71%, P3 = 74%; p < 0.001).
conclusionRoutine environmental cleaning of this neonatal ward was sub-optimal at baseline but improved significantly following a multimodal cleaning intervention. Involving mothers and nursing staff was key to achieving improved environmental and equipment cleaning in this resource-limited neonatal unit.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.