Evidence map›Paper›PMID 33579352›Full record

ArticleStem cell research & therapy2021

Generation of inner ear sensory neurons using blastocyst complementation in a Neurog1

Aleta R Steevens, Matthew W Griesbach, Yun You, James R Dutton, Walter C Low, Peter A Santi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Stem cell research & therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. The making of cells and organs in xenogeneic animal bioreactor.Signal transduction and targeted therapy · 2026
    Review
  2. Review
  3. Article
  4. International journal of stem cells · 2022
    Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Aleta R SteevensDepartment of Ophthalmology, University of Minnesota, Minneapolis, MN, USA. asteeven@umn.edu.ORCID 0000-0001-7104-7816
Matthew W GriesbachDepartment of Otolaryngology, University of Minnesota, Minneapolis, MN, USA.
Yun YouMouse Genetics Laboratory, University of Minnesota, Minneapolis, MN, USA.
James R DuttonStem Cell Institute, University of Minnesota, Minneapolis, MN, USA.
Walter C LowDepartment of Neurosurgery, University of Minnesota, Minneapolis, MN, USA.
Peter A SantiStem Cell Institute, University of Minnesota, Minneapolis, MN, USA.
University of Minnesota · US

Funding

Women's CancerP30CA077598 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Timothy C. Hallstrom · 1998 to 2026
$100.4M
Training Grant: Functional Proteomics of AgingT32AG029796 · NIA · UNIVERSITY OF MINNESOTA · PI EDGAR A ARRIAGA, Douglas G Mashek · 2008 to 2026
$6.6M
Elucidating the role of SOX2 in inner ear developmentF31DC015153 · NIDCD · UNIVERSITY OF ROCHESTER · PI STEEVENS, ALETA RACHEL · 2016 to 2018
$114k
NCI NIH HHS P30 CA077598NIA NIH HHS T32 AG029796NIDCD NIH HHS F31 DC015153
6 · The paper itself

Abstract

This research is the first to produce induced pluripotent stem cell-derived inner ear sensory neurons in the Neurog1

Indexed as

Ear, InnerAnimalsBasic Helix-Loop-Helix ProteinsBlastocystChimeraMiceNerve Tissue ProteinsSensory Receptor CellsBasic Helix-Loop-Helix ProteinsNerve Tissue ProteinsNeurog1 protein, mouseBlastocyst complementationInner earNeurogenin1Regenerative medicineSpiral ganglion neuronsStem cells

Identifiers

PMID33579352
PMCPMC7881691
OpenAlexW3126975282

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.