Evidence map›Paper›PMID 33578935›Full record

ReviewNutrients2021

Impact of Micronutrients on Hypertension: Evidence from Clinical Trials with a Special Focus on Meta-Analysis.

Hui-Fang Chiu, Kamesh Venkatakrishnan, Oksana Golovinskaia, Chin-Kun Wang

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
9.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 68 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Review
  6. Food as Medicine for Hypertension: Microbiota as Mediators.Hypertension (Dallas, Tex. : 1979) · 2025
    Review
  7. Review
  8. Article
  9. Article
  10. Nutrition and Hypertension Researches in 2023: focus on salt intake and blood pressure.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Hui-Fang ChiuDepartment of Chinese Medicine, Taichung Hospital Ministry of Health and Welfare, Taichung 40301, Taiwan.
Kamesh VenkatakrishnanSchool of Nutrition, Chung Shan Medical University, 110, Sec. 1, Jianguo North Road, Taichung 40201, Taiwan.
Oksana GolovinskaiaITMO University, 9, Lomonosova Street, 191002 Saint-Peterburg, Russia.
Chin-Kun WangSchool of Nutrition, Chung Shan Medical University, 110, Sec. 1, Jianguo North Road, Taichung 40201, Taiwan.
Chung Shan Medical University · TWITMO University · RUMinistry of Health and Welfare · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertension (HT) is one of the pivotal risk factors for various detrimental diseases like cardiovascular diseases (CVDs), cerebrovascular disease, and renal dysfunction. Currently, many researchers are paying immense attention to various diet formula (dietary approach) with a special focus on micro and macronutrients along with modified lifestyle and standard anti-hypertensive drugs. Micronutrients (minerals/vitamins) play a central role in the regulation of blood pressure (BP) as they aid the function of macronutrients and also improve the anti-hypertensive functions of some anti-hypertensive agents. Even though several studies have demonstrated the beneficial effects of micronutrients on controlling BP, still some ambiguity exists among the nutritionists/doctors, which combination or individual mineral (dietary approach) contributes to better BP regulation. Therefore, this critical review article was attempted to delineate the underlying role of micronutrients (minerals and vitamins) for the management and prevention or delaying of HT and their related complications with strong affirmation from clinical trials as well as its mechanism of controlling BP. Moreover, the major source and recommended daily allowance (RDA) of various micronutrients are included in this review for guiding common readers (especially HT subjects) and dieticians to choose/recommend a better micronutrient and their combinations (other nutrients and standard anti-hypertensive drugs) for lowering the risk of HT and its related co-morbid conditions like CVDs.

Indexed as

Antihypertensive AgentsBlood PressureCardiovascular DiseasesClinical Trials as TopicDietDietary SupplementsHumansHypertensionMeta-Analysis as TopicMicronutrientsMineralsRecommended Dietary AllowancesRisk FactorsTrace ElementsVitaminsAntihypertensive AgentsMicronutrientsMineralsTrace ElementsVitaminsblood pressureCVDshypertensionmineralsvitamins

Identifiers

PMID33578935
PMCPMC7916651
OpenAlexW3127520621

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.