Evidence map›Paper›PMID 33578901›Full record

ArticleJournal of clinical medicine2021

Is There Pathological Uniformity between the Periphery and Center of a Gastrointestinal Stromal Tumor?

Seong Ji Choi, Kwan Hong Lee, Chan Kyoo Yoo, Jai Hoon Yoon, Ki Seok Jang, Youn Jeong Kim, Hang Lak Lee

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Natural History of Gastric Subepithelial Lesions Measuring 1 to 2 cm.The Korean journal of helicobacter and upper gastrointestinal research · 2026
    Article
  2. Value ofJournal of gastrointestinal oncology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Seong Ji ChoiDepartment of Gastroenterology, Hanyang University Hospital, Seoul 04763, Korea.ORCID 0000-0002-1969-516X
Kwan Hong LeeDepartment of Gastroenterology, Hanyang University Hospital, Seoul 04763, Korea.
Chan Kyoo YooDepartment of Gastroenterology, Hanyang University Hospital, Seoul 04763, Korea.
Jai Hoon YoonDepartment of Gastroenterology, Hanyang University Hospital, Seoul 04763, Korea.
Ki Seok JangDepartment of Pathology, College of Medicine, Hanyang University, Seoul 04763, Korea.
Youn Jeong KimDepartment of Internal Medicine, College of Medicine, The Catholic University of Korea, Incheon ST. Mary's Hospital, Incheon 21431, Korea.ORCID 0000-0001-5870-1801
Hang Lak LeeDepartment of Gastroenterology, Hanyang University Hospital, Seoul 04763, Korea.

Funding

Hanyang University HY-2015
6 · The paper itself

Abstract

backgroundGastrointestinal stromal tumors (GISTs) are mesenchymal tumors and have some malignant potential. Mitotic count is important for predicting the malignant potential of GISTs. Proper treatment of GISTs requires accurate pathological diagnosis. In general, endoscopic ultrasound-guided fine-needle aspiration and deep biopsy are used for pathological diagnosis of GIST before making decisions about surgery. This study sought to evaluate the pathological uniformity of gastric GISTs for mitotic index of the center and periphery of the GIST.

methodsWe retrospectively reviewed the data of 37 gastric GIST patients who underwent wedge resection at Hanyang University Hospital. We used Armed Forces Institute of Pathology criteria to classify gastric GISTs. To determine the pathological uniformity of gastric GISTs, we compared GIST risk stratification between the center and periphery of GISTs.

resultsThe mean size of GISTs was 3.56 ± 2.10 cm. Three lesions were located in the antrum, 11 in the fundus, 9 in the cardia, and 14 in the body. The mean age of patients was 58.65 ± 9.44 years; 18 patients were male and 19 were female. Thirty-five patients (94.6%) showed the same level of risk stratification between the center and periphery of gastric GISTs, while two patients (5.4%) presented different levels of risk between the two sites. No significant difference in mitotic count was observed between the two sites (kappa value = 0.863;

conclusionsMitotic index category (either more than five mitoses per high-power field or five or fewer mitoses per high-power field) of GISTs showed good concurrence between the center and periphery.

Indexed as

gastric gastrointestinal stromal tumorsmitotic countpathological uniformity

Identifiers

PMID33578901
PMCPMC7916709

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.