ArticleAntioxidants (Basel, Switzerland)2021
Flavonol Composition and Antioxidant Activity of Onions (
Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Exploring the Therapeutic Potential ofBiology · 2025Review
- Unlocking the Health Secrets of Onions: Investigating the Phytochemical Power and Beneficial Properties of Different Varieties and Their Parts.Molecules (Basel, Switzerland) · 2025Article
- Green-synthesized natural antioxidants in poultry and livestock feed: enhancing oxidative stability and animal welfare.Frontiers in veterinary science · 2025Review
- Beyond seasoning nutrients bioactive ingredients and healthcare effects of Allium vegetables.Frontiers in nutrition · 2025Review
- Optimization and Validation of Procyanidins Extraction and Phytochemical Profiling of Seven Herbal Matrices of Nutraceutical Interest.Antioxidants (Basel, Switzerland) · 2024Article
- Evidence of synergistic mechanisms of hepatoprotective botanical herbal preparation ofFrontiers in pharmacology · 2024Article
- Bioaccumulation Capacity of Onion (Molecules (Basel, Switzerland) · 2023Article
- Advances in Natural Product Extraction Techniques, Electrospun Fiber Fabrication, and the Integration of Experimental Design: A Comprehensive Review.Molecules (Basel, Switzerland) · 2023Review
- Discrimination of Green Coffee (Antioxidants (Basel, Switzerland) · 2023Article
- Application of Direct Thermal Desorption-Gas Chromatography-Mass Spectrometry for Determination of Volatile and Semi-Volatile Organosulfur Compounds in Onions: A Novel Analytical Approach.Pharmaceuticals (Basel, Switzerland) · 2023Article
- The Classification, Molecular Structure and Biological Biosynthesis of Flavonoids, and Their Roles in Biotic and Abiotic Stresses.Molecules (Basel, Switzerland) · 2023Review
- Optimization of a Microwave Assisted Extraction Method for Maximum Flavonols and Antioxidant Activity of Onion Extracts.Antioxidants (Basel, Switzerland) · 2022Article
- Differences in Antioxidant Potential ofAntioxidants (Basel, Switzerland) · 2022Article
- Valorization of Onion Waste by Obtaining Extracts Rich in Phenolic Compounds and Feasibility of Its Therapeutic Use on Colon Cancer.Antioxidants (Basel, Switzerland) · 2022Article
- A comparison study between ultrasound-assisted and enzyme-assisted extraction of anthocyanins from blackcurrant (Food chemistry: X · 2022Article
- Review
- Antioxidant Properties and Structure-Antioxidant Activity Relationship ofMolecules (Basel, Switzerland) · 2021Review
- Development of Optimized Ultrasound-Assisted Extraction Methods for the Recovery of Total Phenolic Compounds and Anthocyanins from Onion Bulbs.Antioxidants (Basel, Switzerland) · 2021Article
- A Novel Ultrasound-Assisted Extraction Method for the Analysis of Anthocyanins in Potatoes (Antioxidants (Basel, Switzerland) · 2021Article
- Optimization of an Ultrasound-Assisted Extraction Method for the Analysis of Major Anthocyanin Content inMolecules (Basel, Switzerland) · 2021Article
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Authors and funding
7 authors.
Funding
Abstract
The onion is one of the most cultivated and consumed vegetables, and is a very valuable source of antioxidant substances. Every onion variety is rich in flavonols-mainly quercetin derivatives which makes onions the main dietary source of these compounds. This study intends to develop an ultrasound-assisted extraction method (UAE), an economical, green, and efficient technique, that allows us to determine the quality of onion extracts in terms of flavonol composition and antioxidant activity. For this purpose, an ultrasound-assisted extraction method has been optimized to obtain extracts with a high amount of flavonols, as well as with a high antioxidant activity, not only separately using a Box-Behnken design, but also simultaneously, based on multi-response optimization. Multiple response optimization has not only demonstrated an efficacy level similar to that of the individual ones, but it also represents a considerable reduction in terms of cost, time and work. The optimal conditions for simultaneous extractions were determined as follows: 76.8% methanol as an extraction solvent at pH 2 and 58.5 °C temperature, 85% amplitude, 0.9 s cycle, and 0.2:13 g:mL sample mass/solvent volume ratio. Furthermore, the developed method exhibited a high precision level and great recoveries in a rather short extraction time (2 min). These results, together with the development of a fast and simple UHPLC analysis method, lead us to consider the developed UAE method as a suitable technique for the extraction of bioactive compounds from onion matrices.
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