Evidence map›Paper›PMID 33578850›Full record

ArticleVaccines2021

Engineering a Human Plasmacytoid Dendritic Cell-Based Vaccine to Prime and Expand Multispecific Viral and Tumor Antigen-Specific T-Cells.

Kevin Lenogue, Alexandre Walencik, Karine Laulagnier, Jean-Paul Molens, Houssem Benlalam, Brigitte Dreno, Pierre Coulie, Martin Pule, Laurence Chaperot, Joël Plumas

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Frontiers in immunology · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Plasmacytoid Dendritic Cells as a Novel Cell-Based Cancer Immunotherapy.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Kevin LenogueImmunobiology and Immunotherapy of Chronic Diseases, Institute for Advanced Biosciences, INSERM U1209, CNRS UMR 5309, Université Grenoble Alpes, 38700 La Tronche, France.
Alexandre WalencikImmunobiology and Immunotherapy of Chronic Diseases, Institute for Advanced Biosciences, INSERM U1209, CNRS UMR 5309, Université Grenoble Alpes, 38700 La Tronche, France.
Karine LaulagnierPDC*line Pharma, 38701 Grenoble, France.
Jean-Paul MolensImmunobiology and Immunotherapy of Chronic Diseases, Institute for Advanced Biosciences, INSERM U1209, CNRS UMR 5309, Université Grenoble Alpes, 38700 La Tronche, France.
Houssem BenlalamCRCINA, INSERM, Université d'Angers, Université de Nantes, 44011 Nantes, France.
Brigitte DrenoOnco-Dermatology Department, CHU Nantes, CIC 1413, CRCINA, Université de Nantes, 44093 Nantes, France.
Pierre CoulieDe Duve Institute, Université Catholique de Louvain, B-1200 Brussels, Belgium.
Martin PuleCancer Institute, University College London, London WC1E 6BT, UK.
Laurence ChaperotImmunobiology and Immunotherapy of Chronic Diseases, Institute for Advanced Biosciences, INSERM U1209, CNRS UMR 5309, Université Grenoble Alpes, 38700 La Tronche, France.ORCID 0000-0002-1479-9410
Joël PlumasImmunobiology and Immunotherapy of Chronic Diseases, Institute for Advanced Biosciences, INSERM U1209, CNRS UMR 5309, Université Grenoble Alpes, 38700 La Tronche, France.ORCID 0000-0002-5005-4301
Centre National de la Recherche Scientifique · FRde Duve Institute · BEInserm · FRNantes Université · FRUniversity College London · GB

Funding

FP7 People: Marie-Curie Actions FP7-PEOPLE-2009-IEF Proposal n° 251033 - Acronym: PDC Therapy
6 · The paper itself

Abstract

Because dendritic cells are crucial to prime and expand antigen-specific CD8

Indexed as

cancer diseasesimmunotherapyinfectious diseasesplasmacytoid dendritic cellsvaccination

Identifiers

PMID33578850
PMCPMC7916617
OpenAlexW3127684045

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.