Evidence map›Paper›PMID 33578805›Full record

ArticleLife (Basel, Switzerland)2021

Blood Biomarkers to Predict Long-Term Mortality after Ischemic Stroke.

Laura Ramiro, Laura Abraira, Manuel Quintana, Paula García-Rodríguez, Estevo Santamarina, Jose Álvarez-Sabín, Josep Zaragoza, María Hernández-Pérez, Xavier Ustrell, Blanca Lara and 3 more

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Laura RamiroNeurovascular Research Laboratory, Vall d'Hebron Institute of Research (VHIR), Universitat Autònoma de Barcelona, 08035 Barcelona, Spain.ORCID 0000-0002-4121-4609
Laura AbrairaEpilepsy Unit, Neurology Department, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, 08035 Barcelona, Spain.ORCID 0000-0002-5119-7929
Manuel QuintanaEpilepsy Unit, Neurology Department, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, 08035 Barcelona, Spain.ORCID 0000-0003-0288-9088
Paula García-RodríguezNeurovascular Research Laboratory, Vall d'Hebron Institute of Research (VHIR), Universitat Autònoma de Barcelona, 08035 Barcelona, Spain.ORCID 0000-0001-6596-8002
Estevo SantamarinaEpilepsy Unit, Neurology Department, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, 08035 Barcelona, Spain.
Jose Álvarez-SabínDepartment of Medicine, Universitat Autònoma de Barcelona, 08193 Barcelona, Spain.
Josep ZaragozaStroke Unit, Verge de la Cinta University Hospital, 43500 Tortosa, Spain.
María Hernández-PérezStroke Unit, Germans Trias i Pujol University Hospital, 08916 Badalona, Spain.
Xavier UstrellStroke Unit, Joan XXIII University Hospital, 43005 Tarragona, Spain.
Blanca LaraStroke Unit, Bellvitge University Hospital, 08907 Barcelona, Spain.
Mikel TerceñoStroke Unit, Josep Trueta University Hospital, 17007 Girona, Spain.
Alejandro BustamanteNeurovascular Research Laboratory, Vall d'Hebron Institute of Research (VHIR), Universitat Autònoma de Barcelona, 08035 Barcelona, Spain.
Joan MontanerNeurovascular Research Laboratory, Vall d'Hebron Institute of Research (VHIR), Universitat Autònoma de Barcelona, 08035 Barcelona, Spain.

Funding

Instituto de Salud Carlos III IFI17/00012Instituto de Salud Carlos III PI18/00804La Fundació La Marató Reg. 84/240 proj. 201702Spanish stroke research network INVICTUS+ RD16/0019/0021
6 · The paper itself

Abstract

Stroke is a major cause of disability and death globally, and prediction of mortality represents a crucial challenge. We aimed to identify blood biomarkers measured during acute ischemic stroke that could predict long-term mortality. Nine hundred and forty-one ischemic stroke patients were prospectively recruited in the Stroke-Chip study. Post-stroke mortality was evaluated during a median 4.8-year follow-up. A 14-biomarker panel was analyzed by immunoassays in blood samples obtained at hospital admission. Biomarkers were normalized and standardized using

Indexed as

biomarkerendostatinIL-6ischemic strokemortalityTNF-R1

Identifiers

PMID33578805
PMCPMC7916549

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.