Evidence map›Paper›PMID 33578583›Full record

Trial reportMedicine2021

Application of digital practice to improve head movement, visual perception and activities of daily living for subacute stroke patients with unilateral spatial neglect: Preliminary results of a single-blinded, randomized controlled trial.

Ho-Suk Choi, Won-Seob Shin, Dae-Hyouk Bang

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06264713 (Immersive Virtual REality for Treatment of Unilateral Spatial NEglect Due to Stroke Via Eye-tracking Biofeedback), which is not on this map. Cited by 21 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 8 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06264713 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Immersive Virtual REality for Treatment of Unilateral Spatial NEglect Due to Stroke Via Eye-tracking Biofeedback (IRENE Project): a Randomized Controlled Trial

TypeinterventionalSponsorI.R.C.C.S. Fondazione Santa LuciaRan2023 to 2025Enrolled40ConditionsNeglect, Hemispatial, StrokeArmsImmersive Virtual Reality, Sham Immersive Virtual Reality
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 8 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Virtual reality for stroke rehabilitation.The Cochrane database of systematic reviews · 2025
    Pooled it
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  6. Pooled it
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  9. Trial
  10. Review
  11. Article
  12. Article
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  15. Article
  16. Advances in the Rehabilitation of Hemispatial Inattention.Current neurology and neuroscience reports · 2023
    Review
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Ho-Suk ChoiDepartment of Physical Therapy, Asan Institute for Life Sciences, Asan Medical Center, Seoul.
Won-Seob ShinDepartment of Physical Therapy, Collage of Health and Medical Science, Daejeon University, Daejeon.ORCID 0000-0002-6515-7020
Dae-Hyouk BangDepartment of Physical Therapy, Oriental Hospital, Wonkwang University, Ik-San, Republic of Korea.
Asan Medical Center · KRDaejeon University · KRInstitut Icare · CH

Funding

Korea Health Industry Development Institute HI18C2383
6 · The paper itself

Abstract

backgroundVirtual reality (VR) based digital practice is an attractive way to provide a patient engagement, motivation and adaptable environment for stroke rehabilitation. However, clinical evidence of efficacy with VR-based digital practice is very limited. In this study, we investigated the effects of VR-based digital practice program on unilateral spatial neglect (USN) rehabilitation in patients with subacute stroke.

methodsTwenty-four subacute stroke patients with USN were enrolled and randomly assigned to digital practice group (n = 12) and control group (n = 12). Patients in digital practice group received training programs with VR-based applications with leap motion environment. Control group received conventional USN specific training programs. All patients were underwent 4 week practice program (3 sessions/week, a half-hour/session). We analyzed training effects before and after training by assessing the line bisection test, Catherine Bergego Scale, modified Barthel index, Motor-Free Visual Perception Test Vertical Version (MVPT-V), and horizontal head movements (rotation degree and velocity during the VR-based applications), and compared the results between the two groups.

resultsCompared to control group, digital practice group showed significantly greater improvements in the line bisection test (P = .020), and visual perceptual tasks (MVPT-V, responded more on left visual task, P = .024; correctly respond more on both left and right visual tasks, P = .024 and P = .014, respectively; and faster response time, P = .014). Additionally, horizontal head movement of rotation degree and velocity during the VR based practice in the digital practice group were significantly increased more than control group (P = .007 and P = .001, respectively).

conclusionsVR-based digital practice program might be an affordable approach for visual perception and head movement recovery for subacute stroke patients with USN.

Indexed as

Stroke RehabilitationVirtual Reality Exposure TherapyActivities of Daily LivingFemaleHead MovementsHumansMaleMiddle AgedPerceptual DisordersSingle-Blind MethodStrokeTreatment OutcomeVisual Perception

Identifiers

PMID33578583
PMCPMC7886475
OpenAlexW3126494252

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.